Results 41 to 50 of about 31,985 (264)

CNS DEPRESSANT, ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CERTAIN OXANILAMIDE DERIVATIVES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1983
The present study was designed to evaluate the CNS depressant, analgesic and antiinflammatory activity of six N- {D-threo(-)-1-(p-nitrophenyl)-1,3-dihydroxyisopropyl}-N-4-substituted carbamyol-3-hydroxyoxanilamides.
H. El-Bitar
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Neuropharmacological properties of Mikania scandens (L.) Willd. (Asteraceae)

Journal of Advanced Pharmaceutical Technology & Research, 2011
Mikania scandens (L.) Willd. (Asteraceae), known as climbing hemp weed in English, is a herbaceous climbing vine grown as a weed throughout the plains of the Indian subcontinent.
Protapaditya Dey, Sangita Chandra, Priyanka Chatterjee, Sanjib Bhattacharya   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Depression effect of CMC on sulfide ore flotation and its influencing factors

工程科学学报
Depressants are crucial for the selective separation of mineral flotation. Depressants can be classified into organic and inorganic depressants. Inorganic depressants have the disadvantages of toxicity, large dosage, and poor separation efficiency ...
Rong HUANG, Jian LIU, Dong YANG, Xiaoguang YU, Jiamei HAO   +4 more
doaj   +1 more source

Depression behaviors of N-thiourea-maleamic acid and its adsorption mechanism on galena in Mo-Pb flotation separation

International Journal of Mining Science and Technology, 2022
In present study, a novel organic depressant N-thiourea-maleamic acid (TMA) was synthesized and applied as a galena depressant in the flotation separation of Mo-Pb ores. The depression behaviors of TMA were tested through flotation experiments.
Liang Lu, Wei Xiong, Yangge Zhu, Xingrong Zhang, Yongxing Zheng   +4 more
doaj   +1 more source

Epigenetics and depression [PDF]

Dialogues in Clinical Neuroscience, 2019
The risk for major depression is both genetically and environmentally determined. It has been proposed that epigenetic mechanisms could mediate the lasting increases in depression risk following exposure to adverse life events and provide a mechanistic framework within which genetic and environmental factors can be integrated.
Penner-Goeke, S., Binder, E. ; https://orcid.org/0000-0001-7088-6618   +1 more
openaire   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Advances in Flotation Reagents for Cassiterite Separation: Challenges and Sustainable Solutions

Molecules
Tin is a crucial strategic metal, extensively employed in aerospace, new energy materials, and other advanced fields. However, with the progressive depletion of high-grade tin ores, the utilization of low-grade tin ores for metal tin production has ...
Xianchen Wang, Hong Li, Xinhong Liu, Yuan Tang, Chenquan Ni   +4 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source