Results 61 to 70 of about 35,983 (302)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Neuropharmacological properties of Mikania scandens (L.) Willd. (Asteraceae)

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2011
Mikania scandens (L.) Willd. (Asteraceae), known as climbing hemp weed in English, is a herbaceous climbing vine grown as a weed throughout the plains of the Indian subcontinent.
Protapaditya Dey   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Effects of a Depressant Drug as Modified by Experimentally-Induced Expectation

open access: yes, 1964
Objective and subjective reactions to drug and placebo treatments were studied in 15 healthy Ss under three conditions: (1) 200 mg. Pentobarbitone introduced as a depressant drug, (2) 200 mg. Pentobarbitone introduced as a drug the actions of which were
Ragnar Hagdahl   +3 more
core   +1 more source

Depression effect of CMC on sulfide ore flotation and its influencing factors

open access: yes工程科学学报
Depressants are crucial for the selective separation of mineral flotation. Depressants can be classified into organic and inorganic depressants. Inorganic depressants have the disadvantages of toxicity, large dosage, and poor separation efficiency ...
Rong HUANG   +4 more
doaj   +1 more source

Depression behaviors of N-thiourea-maleamic acid and its adsorption mechanism on galena in Mo-Pb flotation separation

open access: yesInternational Journal of Mining Science and Technology, 2022
In present study, a novel organic depressant N-thiourea-maleamic acid (TMA) was synthesized and applied as a galena depressant in the flotation separation of Mo-Pb ores. The depression behaviors of TMA were tested through flotation experiments.
Liang Lu   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

BotIT6: a potent depressant insect toxin from Buthus occitanus tunetanus venom.

open access: yes, 2003
International audienceA new depressant insect toxin Buthus occitanus tunetanus insect-toxin 6 (BotIT6) was purified by high-performance liquid chromatography from Buthus occitanus tunetanus (Bot) venom.
Rochat, Hervé   +9 more
core   +1 more source

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