Results 21 to 30 of about 70,328 (306)
Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]
, 2015 Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad +62 more
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IBRO Neuroscience Reports, 2022 Introduction: Camphor is a popular compound for therapeutic and cosmetic use with a distinctive odour, and somatosensory warming and cooling properties. The mechanisms for its action remain unclear.
Peter M.B. Cahusac, Arunteja Veermalla
doaj +1 more source
Depression and Oral FTC/TDF Pre-exposure Prophylaxis (PrEP) Among Men and Transgender Women Who Have Sex With Men (MSM/TGW). [PDF]
, 2016 We conducted a longitudinal and cross-sectional analysis of depressive symptomology in iPrEx, a randomized, placebo-controlled trial of daily, oral FTC/TDF HIV pre-exposure prophylaxis (PrEP) in men and transgender women who have sex with men. Depression-
Amico, K Rivet +13 more
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The Ethics of Placebo-controlled Trials: Methodological Justifications [PDF]
, 2013 The use of placebo controls in clinical trials remains controversial. Ethical analysis and international ethical guidance permit the use of placebo controls in randomized trials when scientifically indicated in four cases: (1) when there is no proven ...
Grady, Christine, Millum, Joseph
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Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestine [PDF]
, 2004 Background: Herbal preparations like STW 5 (Iberogast(R)) are widely used drugs in the treatment of dyspepsia and motility-related disorders of the gastrointestinal tract.
Allescher, H. D. +6 more
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Development and Validation of eRADAR: A Tool Using EHR Data to Detect Unrecognized Dementia. [PDF]
, 2020 ObjectivesEarly recognition of dementia would allow patients and their families to receive care earlier in the disease process, potentially improving care management and patient outcomes, yet nearly half of patients with dementia are undiagnosed. Our aim
Barnes, Deborah E +7 more
core +2 more sources
Frontiers in Psychiatry, 2023 ObjectiveTo investigate whether depression and exposure to anti-depressant medication are independent risk factors for incident knee surgery and opioid use in knee osteoarthritis (KOA) patients.MethodsWe identified all patients who visited our outpatient
Yongqiang Zheng +7 more
doaj +1 more source
A review on medicinal properties of saffron toward major diseases [PDF]
, 2016 The stigma of Crocus sativus, known as saffron, is one of the most expensive spices in the world. The bioactive components in saffron, picrocrocin, crocin, and safranal, have demonstrated a wide range of uses and capabilities in the medical field.
Abd Razak, Saiful Izwan +4 more
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Biochemistry and Biophysics Reports, 2021 This research was designed to evaluate the CNS depressant, anxiolytic, and analgesic action of aqueous and ethanol extract of Ganoderma applanatum, a valuable medicinal fungus used in multiple disorders belongs to Ganodermataceae family.
S M Moazzem Hossen +5 more
doaj +1 more source
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities. [PDF]
, 2017 Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food.
Jafari, Mahtab +3 more
core +1 more source