Results 61 to 70 of about 1,788,838 (315)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Depression Screening in Adults with Diabetes [PDF]

, 2019
Depression is one of the leading causes of disability worldwide. Screening has long been a part of depression detection in adults in primary care. This screening process, specifically the Patient Health Questionnaire (PHQ), is used for the general ...
Wilson, Whitney
core  

Latent class analysis of actigraphy within the depression early warning (DEW) longitudinal clinical youth cohort

Child and Adolescent Psychiatry and Mental Health
Background Wearable-generated data yield objective information on physical activity and sleep variables, which, are in turn, related to the phenomenology of depression.
Lydia Sequeira, Pantea Fadaiefard, Jovana Seat, Madison Aitken, John Strauss, Wei Wang, Peter Szatmari, Marco Battaglia   +7 more
doaj   +1 more source

Therapeutic alliance in the initial phase of psychotherapy with adolescents: different perspectives and their association with therapeutic outcomes

Research in Psychotherapy, 2016
Psychotherapy research focusing on adults as well as on children and adolescents has revealed a positive association between the quality of the therapeutic alliance (TA) in the first sessions and therapeutic outcomes.
Olga María Fernandez, Mariane Krause, Janet Carola Pérez   +2 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Depression and cancer: physiological and psychological markers [PDF]

, 2010
PhDAim: To investigate potential markers for depression and poor quality of life (QoL) in head and neck (HN) and colorectal (CR) cancer patients. Background: Comorbid depression is strongly related to decreased QoL in cancer patients and may increase ...
Archer, Josephine Astrid
core  

Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression

Translational Psychiatry, 2021
Lithium, a mood stabilizer and common adjunctive treatment for refractory depression, shares overlapping mechanisms of action with ketamine and enhances the duration of ketamine’s antidepressant actions in rodent models at sub-therapeutic doses.
J. Blair Price, Clarissa G. Yates, Brooke A. Morath, Sam K. Van De Wakker, Nathanael J. Yates, Kim Butters, Mark A. Frye, Sean L. McGee, Susannah J. Tye   +8 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Modulatory effects of ketamine on EEG source-based resting state connectivity in treatment resistant depression

Translational Psychiatry
Treatment-resistant depression (TRD) accounts for approximately 30% of major depressive disorder cases and has been characterized by altered functional connectivity within and between the Default Mode (DMN) and Frontoparietal networks (FPN). Ketamine can
Ty Lees, Jason N. Scott, Brian W. Boyle, Shiba M. Esfand, Samantha R. Linton, Courtney Miller, Mohan Li, Sarah E. Woronko, Rebecca Dunayev, Mario Bogdanov, Paula Bolton, Shuang Li, Robert C. Meisner, Diego A. Pizzagalli   +13 more
doaj   +1 more source