Results 221 to 230 of about 354,940 (340)

Mitigating Strain Localization via Stabilized Phase Boundaries for Strengthening Multi‐Principal Element Alloys

Advanced Science, EarlyView.
Strain localization along phase or grain boundaries leads to crack initiation typical of alloys. In multi‐principal element alloys, the enamel‐like microstructure is stabilized by phase boundaries. This facilitates trans‐phase migration of semi‐atomic surfaces and provides sufficient plastic space for dislocation‐mediated deformation.
Jinliang Du, Shukuan Guo, Hangqi Feng, Weijie Li, Zhixin Huang, Zhongji Sun, Yunli Feng, Pei Wang, Ying Li   +8 more
wiley   +1 more source

Development of Carbon‐11 Labeled Pyrimidine Derivatives as Novel Positron Emission Tomography (PET) Agents Enabling Brain Sigma‐1 Receptor Imaging

Advanced Science, EarlyView.
Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai, Ashley Gomm, Chi‐Hyeon Yoo, Prasenjit Mondal, Fleur Marie Lobo, Hui Meng, Yanting Zhou, Weiyao Xie, Hsiao‐Ying Wey, Rudolph E. Tanzi, Can Zhang, Changning Wang, Yu Lan   +12 more
wiley   +1 more source

Present-day antidepressants:new perspectives in general clinical practice (a review)

Терапевтический архив, 2004
S N Mosolov, E G Kostyukova
doaj  

Prevalence of major depressive disorder in Iranian men from 2011 to 2022; a systematic review and meta-analysis. [PDF]

BMC Psychiatry
Hajebi A, Hajiabadi IZ, Fendereski A, Ghodssighassemabadi R, Zamani Hajiabadi A, Hosseini J, Samadaee Gelehkolaee K.   +6 more
europepmc   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Idiopathic Multiple Localized Lipoatrophy Mimicking Amyotrophic Lateral Sclerosis. [PDF]

Cureus
Mashimo S, Matsuoka A, Tanese K, Kano O, Ishiko A.   +4 more
europepmc   +1 more source

On depressions of the wet-bulb thermometer during the hot season at Ahmednuggur, in the Deccan [PDF]

C. Sykes
openalex   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Hemorrhagic Pericardial Effusion Secondary to Coxsackie B Pericarditis. [PDF]

Cureus
Shoukri N, Alakhras H, Strubchevska K, Timmis S.   +3 more
europepmc   +1 more source