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Major depressive disorder [PDF]
Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian +7 more
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BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng +15 more
doaj +1 more source
Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang +15 more
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ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng +6 more
doaj +1 more source
Background: Depressive disorder is a common comorbidity in patients with cardiovascular diseases and is associated with increased hospitalization and death rates.
Zhigao Sun +7 more
doaj +1 more source
Major Depressive Disorder (MDD) and other disorders on the depressive spectrum are more prevalent among HIV-infected individuals than in the general population. These illnesses have a significant impact on prevention, engagement and adherence to HIV care, prognosis, illness-related disability, and quality of life.
FERRARI S +6 more
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Major Depressive Disorder [PDF]
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
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Features of minor depressive disorder subtypes in conditions of COVID-19 pandemic
Background: The continuous research on minor depressive disorder is one of the pressing issues in the context of the COVID-19 pandemic. We studied the features of minor depressive disorder subtypes in conditions of the COVID-19 pandemic.
Shokhrukh Sultanov +4 more
doaj +1 more source
Ethiopathogenesis of Depressive Disorders [PDF]
Etiology of depressive disorders is still unknown. Several factors are involved in its pathophysiology such as neurotransmitters and neuroendocrine alterations, genetics, life events and their appraisal. Some of these components are strictly linked.
Pasquini, M., Berardelli, I., Biondi, M.
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