Results 1 to 10 of about 3,696,874 (383)

Glymphatic dysfunction associated with cortisol dysregulation in major depressive disorder [PDF]

Translational Psychiatry
Cortisol dysregulation plays a critical role in the pathophysiology of depression, but its exact impact on the brain remains unclear. In this cross-sectional study, 210 participants, including 164 depressed patients and 46 healthy controls (HCs), were ...
Shengli Chen, Ziyun Xu, Zheng Guo, Shiwei Lin, Hongyuan Zhang, Qunjun Liang, Qianyun Chen, Yingli Zhang, Bo Peng, Yanzhen Zhao, Gangqiang Hou, Yingwei Qiu   +11 more
doaj   +2 more sources

Personality characteristics, defense styles, borderline symptoms, and non-suicidal self-injury in first-episode major depressive disorder

Frontiers in Psychology, 2023
BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng, Bo Peng, Bo Peng, Jiwu Liao, Yang Li, Guangbo Jia, Jihui Yang, Zhiwei Wu, Jian Zhang, Yingjia Yang, Xinxin Luo, Yao Wang, Yao Wang, Yingli Zhang, Yingli Zhang, Jiyang Pan   +15 more
doaj   +1 more source

Association of Psychiatric History and Type D Personality with Symptoms of Anxiety, Depression, and Health Status Prior to ICD Implantation [PDF]

, 2012
BACKGROUND: Personality factors and psychiatric history may help explain individual differences in risk of psychological morbidity and poor health outcomes in patients with an implantable cardioverter defibrillator (ICD).
Hout, Moniek, Kraaier, Karin, Palen, Job van der, Pedersen, Susanne S., Scholten, Marcoen, Starrenburg, Annemieke H.   +5 more
core   +21 more sources

Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression

Frontiers in Psychiatry, 2021
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang, Xiaodong Cai, Rirang Qiu, Chen Yao, Ye Tian, Chen Gong, Yingli Zhang, Bin Xu, Doudou Zhang, Yu Zang, Jiali Liu, Bo Peng, Luming Li, Luming Li, Luming Li, Luming Li   +15 more
doaj   +1 more source

The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)

PharmacoEconomics (Auckland), 2021
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg, A. Fournier, Tammy Sisitsky, Mark Simes, R. Berman, Sarah H. Koenigsberg, R. Kessler   +6 more
semanticscholar   +1 more source

Aberrant Inter-hemispheric Connectivity in Patients With Recurrent Major Depressive Disorder: A Multimodal MRI Study

Frontiers in Neurology, 2022
ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng, Zhang Yingli, Chen Shengli, Zhou Zhifeng, Peng Bo, Hou Gangqiang, Qiu Yingwei   +6 more
doaj   +1 more source

Molecular pathways of major depressive disorder converge on the synapse

Molecular Psychiatry, 2022
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology. Extensive studies at different molecular levels point to a high complexity of numerous interrelated pathways as the underpinnings of depression. Major
G. Fries, Valeria A Saldana, Johannes Finnstein, T. Rein   +3 more
semanticscholar   +1 more source

Symptoms of Anxiety or Depressive Disorder and Use of Mental Health Care Among Adults During the COVID-19 Pandemic — United States, August 2020–February 2021

MMWR. Morbidity and mortality weekly report, 2021
The spread of disease and increase in deaths during large outbreaks of transmissible diseases is often associated with fear and grief (1). Social restrictions, limits on operating nonessential businesses, and other measures to reduce pandemic-related ...
A. Vahratian, S. Blumberg, Emily P. Terlizzi, Jeannine S. Schiller   +3 more
semanticscholar   +1 more source

C-Reactive Protein as a Biomarker for Major Depressive Disorder?

International Journal of Molecular Sciences, 2022
The etiopathogenesis of depression is not entirely understood. Several studies have investigated the role of inflammation in major depressive disorder. The present work aims to review the literature on the association between C-Reactive Protein (CRP) and
L. Orsolini, S. Pompili, S. Tempia Valenta, V. Salvi, U. Volpe   +4 more
semanticscholar   +1 more source

Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]

, 2020
OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A., Barlow, David H., Bentley, Kate H., Cardona, Nicole, Farchione, Todd J., Nauphal, Maya, Sauer-Zavala, Shannon, Steele, Stephanie Jarvi, Tirpak, Julianne Wilner, Wang, Mengxing   +9 more
core   +2 more sources