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Major depressive disorder [PDF]
Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian +7 more
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BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng +15 more
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Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang +15 more
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ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng +6 more
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Adult Separation Anxiety Disorder in the Geriatric Population with Major Depressive Disorder
Objective: Separation anxiety disorder is a disorder with childhood-onset, which manifests itself also in adulthood and is often comorbid with other psychiatric disorders.
Feride Yıldırım, Aslı Beşirli
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Major Depressive Disorder (MDD) and other disorders on the depressive spectrum are more prevalent among HIV-infected individuals than in the general population. These illnesses have a significant impact on prevention, engagement and adherence to HIV care, prognosis, illness-related disability, and quality of life.
FERRARI S +6 more
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Background: Depressive disorder is a common comorbidity in patients with cardiovascular diseases and is associated with increased hospitalization and death rates.
Zhigao Sun +7 more
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Major Depressive Disorder [PDF]
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
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Ethiopathogenesis of Depressive Disorders [PDF]
Etiology of depressive disorders is still unknown. Several factors are involved in its pathophysiology such as neurotransmitters and neuroendocrine alterations, genetics, life events and their appraisal. Some of these components are strictly linked.
Pasquini, M., Berardelli, I., Biondi, M.
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