Results 1 to 10 of about 3,916,339 (374)

Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit [PDF]

bioRxiv, 2019
Many neuroimaging studies have investigated reward processing dysfunction in major depressive disorder. These studies have led to the common idea that major depressive disorder is associated with blunted responses within the reward circuit, particularly ...
Tommy H. Ng, Lauren B. Alloy, David V. Smith   +2 more
openalex   +2 more sources

Personality characteristics, defense styles, borderline symptoms, and non-suicidal self-injury in first-episode major depressive disorder

Frontiers in Psychology, 2023
BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng, Bo Peng, Bo Peng, Jiwu Liao, Yang Li, Guangbo Jia, Jihui Yang, Zhiwei Wu, Jian Zhang, Yingjia Yang, Xinxin Luo, Yao Wang, Yao Wang, Yingli Zhang, Yingli Zhang, Jiyang Pan   +15 more
doaj   +1 more source

Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression

Frontiers in Psychiatry, 2021
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang, Xiaodong Cai, Rirang Qiu, Chen Yao, Ye Tian, Chen Gong, Yingli Zhang, Bin Xu, Doudou Zhang, Yu Zang, Jiali Liu, Bo Peng, Luming Li, Luming Li, Luming Li, Luming Li   +15 more
doaj   +1 more source

The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)

PharmacoEconomics (Auckland), 2021
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg, A. Fournier, Tammy Sisitsky, Mark Simes, R. Berman, Sarah H. Koenigsberg, R. Kessler   +6 more
semanticscholar   +1 more source

Aberrant Inter-hemispheric Connectivity in Patients With Recurrent Major Depressive Disorder: A Multimodal MRI Study

Frontiers in Neurology, 2022
ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng, Zhang Yingli, Chen Shengli, Zhou Zhifeng, Peng Bo, Hou Gangqiang, Qiu Yingwei   +6 more
doaj   +1 more source

Molecular pathways of major depressive disorder converge on the synapse

Molecular Psychiatry, 2022
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology. Extensive studies at different molecular levels point to a high complexity of numerous interrelated pathways as the underpinnings of depression. Major
G. Fries, Valeria A Saldana, Johannes Finnstein, T. Rein   +3 more
semanticscholar   +1 more source

Symptoms of Anxiety or Depressive Disorder and Use of Mental Health Care Among Adults During the COVID-19 Pandemic — United States, August 2020–February 2021

MMWR. Morbidity and mortality weekly report, 2021
The spread of disease and increase in deaths during large outbreaks of transmissible diseases is often associated with fear and grief (1). Social restrictions, limits on operating nonessential businesses, and other measures to reduce pandemic-related ...
A. Vahratian, S. Blumberg, Emily P. Terlizzi, Jeannine S. Schiller   +3 more
semanticscholar   +1 more source

Association of Psychiatric History and Type D Personality with Symptoms of Anxiety, Depression, and Health Status Prior to ICD Implantation [PDF]

, 2012
BACKGROUND: Personality factors and psychiatric history may help explain individual differences in risk of psychological morbidity and poor health outcomes in patients with an implantable cardioverter defibrillator (ICD).
Hout, Moniek, Kraaier, Karin, Palen, Job van der, Pedersen, Susanne S., Scholten, Marcoen, Starrenburg, Annemieke H.   +5 more
core   +16 more sources

Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

Nature Communications, 2021
Major depressive disorder (MDD) has been shown to be associated with structural abnormalities in a variety of spatially diverse brain regions. However, the correlation between brain structural changes in MDD and gene expression is unclear.
Jiao Li, J. Seidlitz, J. Suckling, Feiyang Fan, Gong-Jun Ji, Yao Meng, Siqi Yang, Kai Wang, J. Qiu, Huafu Chen, W. Liao   +10 more
semanticscholar   +1 more source

Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]

, 2020
OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A., Barlow, David H., Bentley, Kate H., Cardona, Nicole, Farchione, Todd J., Nauphal, Maya, Sauer-Zavala, Shannon, Steele, Stephanie Jarvi, Tirpak, Julianne Wilner, Wang, Mengxing   +9 more
core   +2 more sources