Results 41 to 50 of about 754,068 (197)

Tobacco smoking as a risk factor for major depressive disorder : a population-based study

open access: yes, 2008
Background : Smoking is disproportionately prevalent among people with psychiatric illness. Aims : To investigate smoking as a risk factor for major depressive disorder. Method : A population-based sample of women was studied using case–control and
Berk, Michael   +7 more
core   +1 more source

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]

open access: yes, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
A Bosutti   +189 more
core   +2 more sources

A systematic review and meta-analysis of psychological burden in family caregivers of patients with brain tumors

open access: yesScientific Reports
Family caregivers of brain tumor patients often experience severe psychological problems, with a high prevalence of mental health issues posing a growing challenge in clinical practice.
Haiyu Chen   +7 more
doaj   +1 more source

Anxiety and depression: One, two or three disorders? [PDF]

open access: yesPsihologija, 2004
The study deals with theoretical psychiatric proposals about relations between anxiety and depressive disorders. Three theoretical positions developed on the basis of numerous evidence on relationship of anxiety and depressive disorders: unitaristic ...
Novović Zdenka
doaj   +1 more source

The Patient Health Questionnaire-9 for detection of major depressive disorder in primary care: consequences of current thresholds in a crosssectional study [PDF]

open access: yes, 2010
Background: There is a need for brief instruments to ascertain the diagnosis of major depressive disorder. In this study, we present the reliability, construct validity and accuracy of the PHQ-9 and PHQ-2 to detect major depressive disorder in primary ...
Geerlings, MI   +6 more
core  

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients.

open access: yesPLoS ONE, 2020
ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li   +7 more
doaj   +2 more sources

Glymphatic dysfunction associated with cortisol dysregulation in major depressive disorder

open access: yesTranslational Psychiatry
Cortisol dysregulation plays a critical role in the pathophysiology of depression, but its exact impact on the brain remains unclear. In this cross-sectional study, 210 participants, including 164 depressed patients and 46 healthy controls (HCs), were ...
Shengli Chen   +11 more
doaj   +1 more source

Adequate screening of youngsters for depressive characteristics [PDF]

open access: yes, 2013
Introduction. In order to set up an effective early-detection of depressive symptoms in youngsters, the current study aims to investigate whether two measure moments of the Children's Depression Inventory (CDI) improve screening and whether a multi ...
Braet, Caroline   +4 more
core   +2 more sources

Major Depressive Disorder

open access: yesSouth African Journal of Psychiatry, 2013
The treatment guideline draws on several international guidelines: (i)Practice Guidelines of the American Psychiatric Association (APA)for the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii) Clinical Guidelines for the ...
G Grobler
doaj   +1 more source

Depression and its association with psychological factors among adolescents living with HIV in Southwestern Nigeria

open access: yesBMC Psychiatry, 2023
Objective The aim was to determine the prevalence of depressive disorder and associated psychological factors among adolescents living with HIV/AIDS. Methods One hundred and five adolescents with HIV were assessed for self-esteem, internalized HIV stigma
Lawal RO   +5 more
doaj   +1 more source

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