Results 51 to 60 of about 1,679,263 (303)

Decreased diffusivity along the perivascular spaces in bipolar disorder: an MRI-based cross-sectional and Mendelian randomization study

Translational Psychiatry
The pathophysiology of bipolar disorder (BD) remains unclear. We investigated whether diffusion tensor imaging along perivascular spaces (DTI-ALPS), a putative MRI marker of glymphatic function, is altered in BD and whether this index relates to ...
Zhuohui Chen, Ziwei Teng, Yan Qiu, Sujuan Li, Xuelei Xu, Min Yang, Jindong Chen, Dong Yang, Hao Li   +8 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Anxiety and depression: One, two or three disorders? [PDF]

Psihologija, 2004
The study deals with theoretical psychiatric proposals about relations between anxiety and depressive disorders. Three theoretical positions developed on the basis of numerous evidence on relationship of anxiety and depressive disorders: unitaristic ...
Novović Zdenka
doaj   +1 more source

Depressive disorders.

American family physician, 2004
[no abstract available]
Geddes J. R., Butler R., Hatcher S., CIPRIANI, Andrea, BARBUI, Corrado, Price J., Carney S., Von Korff M.   +7 more
openaire   +7 more sources

Folate for depressive disorders [PDF]

Cochrane Database of Systematic Reviews, 2003
There are a number of effective interventions for the treatment of depression. It is possible that the efficacy of these treatments will be improved further by the use of adjunctive therapies such as folate.1. To determine the effectiveness of folate in the treatment of depression 2.
Taylor, M, Carney, S, Geddes, J, Goodwin, G   +3 more
openaire   +2 more sources

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

A systematic review and meta-analysis of psychological burden in family caregivers of patients with brain tumors

Scientific Reports
Family caregivers of brain tumor patients often experience severe psychological problems, with a high prevalence of mental health issues posing a growing challenge in clinical practice.
Haiyu Chen, Tianxiang Zou, Ziwei Teng, Yue Qin, Yizhi Deng, Renrong Wu, Jing Huang, Qiong Luo   +7 more
doaj   +1 more source

Pharmacological management of major depressive disorder

, 2022
Major depressive disorder [MDD] is a highly prevalent psychiatric disorder that causes significant impairment in different areas of one's life. There are multiple factors contributing to the development of MDD including genetic, environmental, and ...
Ojiako, Chiamaka Priscilla
core  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source