Results 71 to 80 of about 1,946,485 (301)

Predictive value of bipolar-spectrum clinical features in a large cohort of fluoxetine treated patients with major depressive disorder [PDF]

, 2011
Objective: The presence of unrecognized bipolar disorder or “bipolar spectrum” features has been suggested to contribute to poor treatment response in major depressive disorder.
CASAMASSIMA, FRANCESCO
core  

Prevalence of depressive disorder among elderly people in China： a Meta-analysis

Sichuan jingshen weisheng
BackgroundDepressive disorder is one of the most common mental disorders in the elderly and the existing meta-analyses on the prevalence of depressive disorder among the elderly have mainly summarized the findings from patient self-rating scales or ...
Wu Ping, Huang Guangbiao, Tan Zhonglin, Wu Yue, Liang Sugai   +4 more
doaj   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Potential of niacin skin flush response in adolescent depression identification and severity assessment: a case-control study

BMC Psychiatry
Background The diagnosis of adolescent Depressive Disorder (DD) lacks specific biomarkers, posing significant challenges. This study investigates the potential of Niacin Skin Flush Response (NSFR) as a biomarker for identifying and assessing the severity
Jie Feng, Wenjiao Min, Dandan Wang, Jing Yuan, Junming Chen, Lisha Chen, Wei Chen, Meng Zhao, Jia Cheng, Chunling Wan, Bo Zhou, Yulan Huang, Yaoyin Zhang   +12 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

Journal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan, Chris LaVallee, Keshia Maughn, Santosh Balakrishnan, Jacqueline A Pesa, Kruti Joshi, Craig Nelson   +6 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Decreased gyrification in major depressive disorder

, 2009
Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder.
Yu, Chunshui, Zhang, Yuanchao, Jiang, Tianzi, Li, Kuncheng, T. Z. Jiang, Li, Chong, Zhou, Yuan   +6 more
core  

Bipolar and major depressive disorders: associations with serum zonulin levels and rs2070937 polymorphism

BMC Psychiatry
Background The underlying pathophysiology of bipolar disorder and major depressive disorder is not fully understood. Inflammation is increasingly recognized as a contributing factor. The gut plays a central role in this process.
Ozgur Baykan, Furkan Akbas, Ayla Solmaz Avcikurt, Hayriye Baykan   +3 more
doaj   +1 more source