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Major Depressive Disorder in a Preschooler
Journal of the American Academy of Child Psychiatry, 1985The history and evaluation of a preschool child who meets criteria for major depressive disorder are reported. In addition to describing the multifaceted workup required, the authors acknowledge the developmental issues which makes the diagnosis of depression difficult in this age group.
Gabrielle A. Carlson, Javad H. Kashani
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Hypersomnia in major depressive disorders
Journal of Affective Disorders, 1984Hypersomnia was experienced by 17 of 102 patients with major depressive disorder. Comparisons between hypersomnic and non-hypersomnic depressives demonstrated significant associations between hypersomnia and increased appetite, weight gain, agitation, headaches, depression in a first-degree relative, and earlier age of illness onset.
Dan M Mungas +2 more
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2014
Depression affects about 121 million people worldwide and is characterized by episodes of affective, somatic, cognitive, and motivational symptoms generally expressed by loss of interest and pleasure with increasing functional impairment, morbidity, and mortality.
Stefano Baroni +3 more
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Depression affects about 121 million people worldwide and is characterized by episodes of affective, somatic, cognitive, and motivational symptoms generally expressed by loss of interest and pleasure with increasing functional impairment, morbidity, and mortality.
Stefano Baroni +3 more
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Migraine symptomatology and major depressive disorder
Cephalalgia, 2010Introduction and objective: Migraine and major depressive disorder (MDD) frequently co-occur, but it is unclear whether depression is associated with a specific subtype of migraine. The objective of this study was to investigate whether migraine is qualitatively different in MDD patients ( N = 1816) and non-depressed controls ( N = 3428).
Dale R. Nyholt +9 more
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Abstract This chapter looks at the section on Major Depressive Disorder in the Anxiety and Related Disorders Interview Schedule for DSM-5, Child Version: Parent Interview Schedule (PIS). If the parent responds “Yes” to Question 1a and “No” to Question 1b (parent reports past depression but denies current episode), the interviewer should ...
Anne Marie Albano, Wendy K. Silverman
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Anne Marie Albano, Wendy K. Silverman
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MicroRNAs in Major Depressive Disorder
2019Major depressive disorder (MDD) is a severe and chronic psychiatric disorder with a high prevalence in the population. Although our understanding of its pathophysiological mechanisms has significantly increased over the years, available treatments still present several limitations and are not effective to all MDD patients.
Deborah Benevenuto +3 more
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Epigenetics of Major Depressive Disorder
2020Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several psychiatric disorders.
Wang K. Z. +6 more
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Ketamine for Major Depressive Disorder
2023Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Conventional antidepressant treatment is characterised by a significant time to onset of therapeutic action (approximately 2 weeks) and fails to achieve a stable remission of symptoms in one-third of subjects with MDD.
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Hormones and Major Depressive Disorder
2019Hormonal influences figure prominently in the development of major depressive disorder (MD). The chapter addresses the hypothalamic-pituitary-adrenal (HPA) axis and gonadal (i.e., estrogen and testosterone) hormones that are most relevant to MD. There is substantial evidence of HPA dysfunction in persons with MD, including adrenal hypersensitivity ...
Mark A. Ellenbogen +2 more
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