Results 91 to 100 of about 83,135 (307)

Water‐Stable Paper‐Based Laser‐Induced Graphene With Asymmetric Water Adhesion and Wettability

open access: yesAdvanced Materials Interfaces, EarlyView.
Paper‐based electronics are attractive for sustainable and disposable devices, but often fail in wet environments. By introducing Parafilm into cellulose paper combined with laser conversion, two graphene surfaces with different water interactions are created.
Lingyin Meng   +3 more
wiley   +1 more source

Risperidone Augmentation in Antidepressant-Resistant Somatic Symptom Disorder

open access: yesPsychiatry and Clinical Psychopharmacology
Chronic somatic symptoms are hallmarks of somatic symptom disorder (SSD), characterized by notable disruptions in the day to day lives of affected patients.
Eun Hyun Seo   +2 more
doaj   +1 more source

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

open access: yesGeneral Psychiatry, 2019
Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as ...
Aditya Somani, Sujita Kumar Kar
doaj   +1 more source

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

open access: yesAdvanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen   +11 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial. [PDF]

open access: yes, 2019
ObjectiveLatino immigrants experience acculturative stress and increased depression risk. Mindfulness meditation improves depressive symptoms, yet the vast majority of research has focused on English speaking populations.MethodsIn this randomized ...
Irwin, Michael R   +2 more
core   +2 more sources

A new therapy modality for treatment-resistant depression: Vagal nerve stimulation

open access: yesPsychiatry and Behavioral Sciences, 2014
Objective: Although new treatment modalities are recommended for the treatment resistant depression, it has been estimated that some depressive episodes treated for an adequate duration with recommended dose of an antidepressant exhibit treatment ...
Visal Buturak, Bulent Bakar
doaj   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

open access: yesAdvanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang   +15 more
wiley   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

open access: yes, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P   +8 more
core   +1 more source

Case report: two cases of rhabdomyolysis following esketamine treatment

open access: yesFrontiers in Psychiatry
Major depressive disorder is a mental disorder affecting millions of people worldwide. A considerable proportion of patients demonstrate a lack of response to conventional treatment.
René Zeiss   +3 more
doaj   +1 more source

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