Depressive disorder, treatment-resistant

Results 151 to 160 of about 39,697 (260)

Revisiting Thyroid Function in Patients Undergoing Electroconvulsive Therapy for Severe or Treatment-Resistant Depression. [PDF]

J Clin Med
Mutlu E, Bahçecioğlu AB, Gürel ŞC.
europepmc +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source

Celecoxib adjunct to antidepressants for major depressive disorder: Systematic review and meta-analysis. [PDF]

Brain Behav Immun Health
Srisurapanont M, Suradom C, Suttajit S.
europepmc +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke +2 more
wiley +1 more source

Revisiting the prevalence of bipolar disorder: implications of a broader spectrum model. [PDF]

Front Psychiatry
Kreinin A.
europepmc +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le +8 more
wiley +1 more source

Structural and functional neuroimaging correlates of suicidal ideation in treatment-resistant major depressive disorder. [PDF]

Int J Neuropsychopharmacol
Burhunduli P +4 more
europepmc +1 more source

Experiencing Extreme Hunger in Anorexia Nervosa Recovery: A Qualitative Analysis of Reddit Narratives

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Recovery from anorexia nervosa involves psychological and social adjustments that extend beyond weight restoration. Online forums increasingly serve as spaces where recovery experiences are openly shared, including accounts of “extreme hunger” during refeeding—a phenomenon that has not been reported in the clinical literature.
Léonie Langanay +6 more
wiley +1 more source

Case Report: Right-sided vagus nerve stimulation for treatment-resistant affective disorders with complex cardiac comorbidity. [PDF]

Front Psychiatry
Licht C, Landgrebe M, Pieper T.
europepmc +1 more source

Daily Ovarian Hormone Exposure and Loss of Control Eating in Adolescent Girls: A Stage 2 Registered Report

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This Stage 2 Registered Report examined (1) the main effects and interaction of within‐person daily associations between ovarian hormones (i.e., estrogen, progesterone) and loss of control eating (LOCE), and (2) the within‐person mediating roles of food‐related reward anticipation and response inhibition. Methods Adolescent girls (n =
Tyler B. Mason +4 more
wiley +1 more source

major depressive disorder
treatment-resistant depression
esketamine

treatment-resistant
ketamine
depressive disorder

depression
treatment resistant depression
medicine