Ketamine or Esketamine in Special Populations of Patients With Treatment-Resistant Depression. [PDF]
Grabarczyk Ł +3 more
europepmc +1 more source
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès +30 more
wiley +1 more source
Ketamine as an NMDA-modulating therapy in bipolar disorder: rationale and evidence. [PDF]
Queissner R +2 more
europepmc +1 more source
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie +10 more
wiley +1 more source
Evaluation of Current Evidence on the Efficacy of Esketamine in Treating Substance-Use Disorders in Patients With Treatment-Resistant Depression (TRD): A Narrative Review. [PDF]
Shelke S, Thummalapally RR.
europepmc +1 more source
Abstract Understanding the mechanisms underlying post‐traumatic epilepsy (PTE) following traumatic brain injury (TBI), and developing strategies to prevent or modify its progression, has been the focus of large collaborative efforts within the epilepsy and TBI research communities for over a decade.
Elisa R. Zanier +82 more
wiley +1 more source
Pharmacological Management, Safety, and Outcomes in Bipolar Disorder: An Integrated Narrative Review of Clinical and Translational Evidence. [PDF]
Bereda G.
europepmc +1 more source
Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations
Abstract Ring chromosome 20 (ring 20) is a rare genetic condition usually presenting as developmental and epileptic encephalopathy. The disease is caused by fusion of the long and short arms of chromosome 20. Patients are symptomatic even if there is no loss of genetic material.
Asma Khamis +8 more
wiley +1 more source
Antidepressant Augmentation of Antipsychotic Treatment in Schizophrenia: A Narrative Review. [PDF]
Li W +7 more
europepmc +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source

