Results 221 to 230 of about 39,697 (260)

Moderate exercise improves depression parameters in treatment-resistant patients with major depressive disorder

Journal of Psychiatric Research, 2011
Treatment-resistant major depressive disorder (MDD) is a complex condition, with very low remission rates. Physical exercise has been used, with some encouraging results, as an alternative therapy in other depressive disorders. This study assessed the impact on depression and functioning parameters of a moderate intensity exercise program, as an ...
Jorge Mota-Pereira, Serafim Carvalho, JOSÉ CARLOS Ribeiro   +2 more
exaly   +4 more sources

Pharmacotherapy for the treatment of depression in patients with alzheimer’s disease: a treatment-resistant depressive disorder

Expert Opinion on Pharmacotherapy, 2018
Pharmacotherapy for the treatment of depressive disorders in Alzheimer's Disease (AD) represents a clinical challenge. pharmacological options are often attempted after a period of watchful waiting (8-12 weeks). monoaminergic antidepressant drugs have shown only modest or null clinical benefits, maybe because the etiology of depressive symptoms in ad ...
Madia Lozupone, Maddalena La Montagna, Francesca D’Urso, Carla Piccininni, Rodolfo Sardone, Vittorio Dibello, Gianluigi Giannelli, Vincenzo Solfrizzi, Antonio Greco, Antonio Daniele, Nicola Quaranta, Davide Seripa, Antonello Bellomo, Giancarlo Logroscino, Francesco Panza   +14 more
openaire   +3 more sources

Augmentation of antidepressants with perospirone for treatment-resistant major depressive disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009
We examined the efficacy and tolerability of perospirone, a dopamine D2 and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist, in the augmentation of antidepressant treatment of partially responding and nonresponding patients with major depressive disorder.
Yasushi, Sato, Norio, Yasui-Furukori, Taku, Nakagami, Manabu, Saito, Sunao, Kaneko   +4 more
openaire   +2 more sources

The combination of duloxetine and bupropion for treatment-resistant major depressive disorder

Depression and Anxiety, 2006
Our objective was to assess the effectiveness and safety of the combination of duloxetine and bupropion for treatment-resistant major depressive disorder (TRD). A retrospective chart review was conducted to identify patients with major depressive disorder (MDD) who had not experienced full remission of symptoms following an adequate trial of either ...
George I, Papakostas, John J, Worthington, Dan V, Iosifescu, Gustavo, Kinrys, Alana M, Burns, Lauren B, Fisher, Caitlin H, Homberger, David, Mischoulon, Maurizio, Fava   +8 more
openaire   +2 more sources

Pramipexole augmentation in treatment-resistant major depressive disorder

Expert Review of Neurotherapeutics, 2013
Evaluation of: Cusin C, Iovieno N, Iosifescu DV et al. A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder. J. Clin. Psychiatry 74(7), e636-e641 (2013). To overcome limited efficacy in antidepressants, clinicians may choose augmentation, switching to a different ...
openaire   +2 more sources

Mismatch negativity in treatment-resistant depression and borderline personality disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2010
Cognitive dysfunctions, such as attentional impairment, are central features of both treatment-resistant depression (TRD) and borderline personality disorder (BPD). The treatment failure of TRD due to its comorbidity with BPD is debated in the literature.
Wei, He, Hao, Chai, Leilei, Zheng, Wenjun, Yu, Wanzhen, Chen, Jianming, Li, Wei, Chen, Wei, Wang   +7 more
openaire   +2 more sources

Use of atypical antipsychotics for treatment-resistant major depressive disorder

Current Psychiatry Reports, 2008
Despite the progressive increase in the number of pharmacologic agents with potential antidepressant activity, many patients suffering from major depressive disorder (MDD) continue to be symptomatic. Clearly, an urgent need exists to develop safer, better tolerated, and more effective treatments for MDD.
George I, Papakostas, Richard C, Shelton
openaire   +2 more sources

Direct and indirect costs of employees with treatment-resistant and non-treatment-resistant major depressive disorder

Current Medical Research and Opinion, 2010
Treatment-resistant depression (TRD) imposes substantial cost from the perspective of employers. The objective of this study was to assess direct healthcare costs and indirect (disability and medical-related absenteeism) costs associated with TRD compared with non-treatment-resistant major depressive disorder (MDD).Employees with one or more inpatient,
Jasmina I, Ivanova, Howard G, Birnbaum, Yohanne, Kidolezi, Ganesh, Subramanian, Sajjad A, Khan, Michael D, Stensland   +5 more
openaire   +2 more sources

[Major depressive disorder and treatment-resistant depression: an epidemiological analysis in Argentina of the Study of Treatment-Resistant Depression in Latin America].

Vertex (Buenos Aires, Argentina), 2022
Treatment-Resistant Depression (TRD) prevalence varies considerable between regions and epidemiology of TRD in Argentina is lacking. Based on the Treatment-Resistant Depression in America Latina (TRAL) study, epidemiology and burden of TRD in MDD patients from Argentina is reported in this paper.
Gerardo, García Bonetto, Ricardo Marcelo, Corral, Christian, Lupo, Manuel, Vilapriño Duprat, Hernán, Alessandria, Gabriela, Kanevsky, Patricia, Cabrera   +6 more
openaire   +1 more source

Choosing death in depression: a commentary on ‘Treatment-resistant major depressive disorder and assisted dying’

Journal of Medical Ethics, 2015
Schuklenk and van de Vathorst's paper is a very welcome addition to the literature on the assisted dying debate and will be of great interest to clinicians working in the field of mental health.1 Many psychiatrists will have had patients who have asked them to allow them to die, to desist in their efforts to prevent their suicide, and one of us has had
Matthew R, Broome, Angharad, de Cates
openaire   +2 more sources