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The ‘Dalhousie Serotonin cocktail’ for treatment-resistant major depressive disorder
Journal of Psychopharmacology, 2001We describe the successful treatment of five patients with treatment-resistant major depressive disorder (TR-MDD) with a combination pharmacotherapy of pindolol, tryptophan and nefazodone. Five TR-MDD outpatients who had previously not responded to at least four different antidepressant medication trials were initiated on 300 mg/day of nefazodone, 7.5 ...
Serdar Dursun +2 more
exaly +3 more sources
Journal of Psychiatric Research, 2011
Treatment-resistant major depressive disorder (MDD) is a complex condition, with very low remission rates. Physical exercise has been used, with some encouraging results, as an alternative therapy in other depressive disorders. This study assessed the impact on depression and functioning parameters of a moderate intensity exercise program, as an ...
Ribeiro J +2 more
exaly +4 more sources
Treatment-resistant major depressive disorder (MDD) is a complex condition, with very low remission rates. Physical exercise has been used, with some encouraging results, as an alternative therapy in other depressive disorders. This study assessed the impact on depression and functioning parameters of a moderate intensity exercise program, as an ...
Ribeiro J +2 more
exaly +4 more sources
Brexpiprazole for treatment-resistant major depressive disorder
Expert Opinion on Pharmacotherapy, 2019Introduction:Treatment-resistant depression (TRD), seldom interchangeably referred to as 'depression inadequately responding to the standard antidepressant drug,' carries a significant burden. The atypical antipsychotics represent a popular augmentation strategy for antidepressant-resistant depression, although their efficacy/safety profiles vary ...
Fornaro M. +4 more
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Axis III disorders in treatment-resistant major depressive disorder
Psychiatry Research, 2003A number of naturalistic studies have found that medical co-morbidity conveys a worse long-term prognosis in the treatment of major depressive disorder (MDD). The purpose of this study was to test whether the presence of co-morbid medical conditions can predict clinical response in patients with treatment-resistant MDD (TRD) treated with open-label ...
George I, Papakostas +7 more
openaire +2 more sources
The bipolar diathesis of treatment-resistant major depressive disorder
International Journal of Psychiatry in Clinical Practice, 2008Objective. In this study, we determined the prevalence of bipolarity in patients with treatment-resistant depression (TRD) by investigating demographic and clinical characteristics, diagnostic subtypes and illness outcome of patients with resistant depression. Methods.
Young Sup, Woo +4 more
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Intravenous Ketamine for Treatment-Resistant Major Depressive Disorder
Annals of Pharmacotherapy, 2012OBJECTIVE: To evaluate the literature regarding the efficacy and safety of intravenous ketamine for treatment-resistant major depressive disorder (MDD). DATA SOURCES: A MEDLINE search (1966-September 2011) was performed using the terms
Jordan R, Covvey +2 more
openaire +2 more sources

