CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
Clinical Pharmacology &Therapeutics, EarlyView.CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source
The Montreal model of ketamine-therapy for alcohol use disorder and comorbid treatment-resistant depression: protocol for a feasibility trial. [PDF]
BMJ OpenMcAnulty C +12 more
europepmc +1 more source
Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review
Clinical Pharmacology &Therapeutics, EarlyView.Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović +4 more
wiley +1 more source
A scoping review of mystical-type experiences and mood symptom outcomes in psychedelic therapy clinical trials: comparing life-threatening disease and depressive populations. [PDF]
Ther Adv PsychopharmacolDeutsch A +3 more
europepmc +1 more source
07 - NON-PHARMACOLOGICAL STRATEGIES IN TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER [PDF]
, 2019 Serafim Carvalho +3 more
openaire +1 more source
Resilience Practices and Post‐Traumatic Growth Among Sudanese IDPs
Conflict Resolution Quarterly, EarlyView.ABSTRACT In this paper we examine the resilience of internally displaced persons (IDPs) in Sudan who have endured various forms of suffering resulting from being targeted or trapped by militants involved in large‐scale violence. Upon escaping the conflict zones, the civilians exhibit strength, adaptability, and wisdom in the face of various threats to ...
Karina Korostelina +2 more
wiley +1 more source
Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder: From Bench to Bedside-A Scoping Review of Neurobiological Mechanisms and Clinical Translation. [PDF]
Bioengineering (Basel)Trandafir DM +4 more
europepmc +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Inpatient treatment aimed at weight restoration and psychiatric stabilization is often required for individuals with anorexia nervosa (AN). This study aimed to identify distinct trajectories of change in body mass index (BMI) and depressive symptoms during inpatient treatment, examine clinical predictors and outcomes, and test ...
Matteo Martini +5 more
wiley +1 more source
A Promise Without Panacea: Psychedelic-Assisted Therapies in Modern Psychiatry. [PDF]
CureusRaza M, Kaur J.
europepmc +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk +5 more
wiley +1 more source