Results 61 to 70 of about 83,135 (307)

Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder [PDF]

International Journal of Environmental Research and Public Health, 2018
Objectives: Extant evidence indicates that ketamine exerts rapid antidepressant effects in treatment-resistant depressive (TRD) symptoms as a part of major depressive disorder (MDD) and bipolar disorder (BD). The identification of depressed sub-populations that are more likely to benefit from ketamine treatment remains a priority.
Carola Rong, Caroline Park, Joshua D. Rosenblat, Mehala Subramaniapillai, Hannah Zuckerman, Dominika Fus, Yena L. Lee, Zihang Pan, Elisa Brietzke, Rodrigo B. Mansur, Danielle S. Cha, Leanna M. W. Lui, Roger S. McIntyre   +12 more
openaire   +3 more sources

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P, Headrick, John P., Neumann, David L., Peart, Jason N., Shum, David H K, Stapelberg, Nicolas J C   +5 more
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

Advanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

The FDA “black box” warning on antidepressant suicide risk in young adults: More harm than benefits? [PDF]

, 2019
The decision made in the year 2004 by the U.S. Food and Drug Administration (FDA) to require a boxed warning on antidepressants regarding the risk of suicidality in young adults still represents a matter of controversy.
Anastasia A., Carano A., De Berardis D., Di Giannantonio M., Fornaro M., Martinotti G., Natale S. D., Olivieri L., Orsolini L., Perna G., Rapini G., Valchera A., Vellante F.   +12 more
core   +1 more source

The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive–compulsive disorder: a comparative study with other treatment-resistant mental disorders

BMC Psychiatry
Background This study investigates the role of genetic variations in the 5-Hydroxytryptamine Receptor 2A (HTR2A) gene in subjects with treatment-resistant obsessive–compulsive disorder (TR-OCD), compared to individuals with other treatment-resistant ...
Antonio Del Casale, Giovanna Gentile, Jan Francesco Arena, Martina Nicole Modesti, Clarissa Zocchi, Serena Mancino, Ottavia De Luca, Gloria Angeletti, Stefano Ferracuti, Robert Preissner, Maurizio Pompili, Maurizio Simmaco, Marina Borro   +12 more
doaj   +1 more source

Enhanced Li‐Ion Battery Performance with Hybrid MXene/GnR Electrodes: Heterojunctions and Engineered Architectures Supported by DFT Mechanistic Studies for Improved Rate Performance, Stability & Capacity

Advanced Functional Materials, EarlyView.
Lithium‐ion batteries (LIBs) remain central to energy storage but suffer from slow ion transport and degradation. Here, we present a binder‐free Ti3C2Tx MXene/GnR hybrid electrode with a porous 3D architecture formed via freeze casting. The structure enhances conductivity, ion transport, and stability, delivering 401 mAh/g, ∼97% efficiency, and 92 ...
Sara Mohseni Taromsari, Meysam Salari, Dipali Nayak, Saeed Habibpour, Ling Wei Hwang, Cristopher Carreiro, Carlos M. Da Silva, Aiping Yu, Chul B. Park, Cristina H. Amon, Hani E. Naguib   +10 more
wiley   +1 more source

Prominent autistic traits and subthreshold bipolar/mixed features of depression in severe anorexia nervosa [PDF]

, 2019
Autistic traits are associated with a burdensome clinical presentation of anorexia nervosa (AN), as is AN with concurrent depression. The aim of the present study was to explore the intertwined association between complex psychopathology combining ...
Anastasia, Annalisa, de Bartolomeis, Andrea, Fornaro, Michele, Fusco, Andrea, Novello, Stefano, Sassi, Teresa, Senatore, Ignazio   +6 more
core   +1 more source

Transdermal Scopolamine for Treatment-Resistant Major Depressive Disorder

Cureus
Conventional antidepressants are useful in the treatment of major depressive disorder (MDD) but are limited by their delayed onset of action and lack of adequate therapeutic response in approximately one-third of patients. This has led to a quest for faster-acting and more effective antidepressants.
Liester, Mitchell B, Shash, Delia S
openaire   +2 more sources