Results 11 to 20 of about 3,534,144 (421)
BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng+15 more
doaj +1 more source
Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang+15 more
doaj +1 more source
ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng+6 more
doaj +1 more source
The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg+6 more
semanticscholar +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song+11 more
wiley +1 more source
Molecular pathways of major depressive disorder converge on the synapse
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology. Extensive studies at different molecular levels point to a high complexity of numerous interrelated pathways as the underpinnings of depression. Major
G. Fries+3 more
semanticscholar +1 more source
The spread of disease and increase in deaths during large outbreaks of transmissible diseases is often associated with fear and grief (1). Social restrictions, limits on operating nonessential businesses, and other measures to reduce pandemic-related ...
A. Vahratian+3 more
semanticscholar +1 more source
Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications
Major depressive disorder (MDD), also referred to as depression, is one of the most common psychiatric disorders with a high economic burden. The etiology of depression is still not clear, but it is generally believed that MDD is a multifactorial disease
Zezhi Li+3 more
semanticscholar +1 more source
Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]
OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A.+9 more
core +2 more sources
Ethiopathogenesis of Depressive Disorders [PDF]
Etiology of depressive disorders is still unknown. Several factors are involved in its pathophysiology such as neurotransmitters and neuroendocrine alterations, genetics, life events and their appraisal. Some of these components are strictly linked.
Pasquini, M., Berardelli, I., Biondi, M.
openaire +4 more sources