Results 11 to 20 of about 3,534,144 (421)

Personality characteristics, defense styles, borderline symptoms, and non-suicidal self-injury in first-episode major depressive disorder

open access: yesFrontiers in Psychology, 2023
BackgroundNon-suicidal self-injury (NSSI) is commonly seen in adolescents with depression and is a high-risk factor leading to suicide. The psychological mechanisms underlying depression with NSSI are still unclear.
Bo Peng   +15 more
doaj   +1 more source

Case Report: Lateral Habenula Deep Brain Stimulation for Treatment-Resistant Depression

open access: yesFrontiers in Psychiatry, 2021
Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) is a promising therapy for TRD patients. However, its safety and efficacy are still unclear.
Zhiyan Wang   +15 more
doaj   +1 more source

Aberrant Inter-hemispheric Connectivity in Patients With Recurrent Major Depressive Disorder: A Multimodal MRI Study

open access: yesFrontiers in Neurology, 2022
ObjectiveInter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ...
Guo Zheng   +6 more
doaj   +1 more source

The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)

open access: yesPharmacoEconomics (Auckland), 2021
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg   +6 more
semanticscholar   +1 more source

A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song   +11 more
wiley   +1 more source

Molecular pathways of major depressive disorder converge on the synapse

open access: yesMolecular Psychiatry, 2022
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology. Extensive studies at different molecular levels point to a high complexity of numerous interrelated pathways as the underpinnings of depression. Major
G. Fries   +3 more
semanticscholar   +1 more source

Symptoms of Anxiety or Depressive Disorder and Use of Mental Health Care Among Adults During the COVID-19 Pandemic — United States, August 2020–February 2021

open access: yesMMWR. Morbidity and mortality weekly report, 2021
The spread of disease and increase in deaths during large outbreaks of transmissible diseases is often associated with fear and grief (1). Social restrictions, limits on operating nonessential businesses, and other measures to reduce pandemic-related ...
A. Vahratian   +3 more
semanticscholar   +1 more source

Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications

open access: yesNeuroscience Bulletin, 2021
Major depressive disorder (MDD), also referred to as depression, is one of the most common psychiatric disorders with a high economic burden. The etiology of depression is still not clear, but it is generally believed that MDD is a multifactorial disease
Zezhi Li   +3 more
semanticscholar   +1 more source

Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]

open access: yes, 2020
OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A.   +9 more
core   +2 more sources

Ethiopathogenesis of Depressive Disorders [PDF]

open access: yesClinical Practice & Epidemiology in Mental Health, 2014
Etiology of depressive disorders is still unknown. Several factors are involved in its pathophysiology such as neurotransmitters and neuroendocrine alterations, genetics, life events and their appraisal. Some of these components are strictly linked.
Pasquini, M., Berardelli, I., Biondi, M.
openaire   +4 more sources

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