Results 11 to 20 of about 3,696,874 (383)

Major Depressive Disorder

open access: yesSouth African Journal of Psychiatry, 2013
The treatment guideline draws on several international guidelines: (i)Practice Guidelines of the American Psychiatric Association (APA)for the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii) Clinical Guidelines for the ...
G Grobler
doaj   +3 more sources

Major Depressive Disorder [PDF]

open access: bronzeNeuron, 2000
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Maurizio Fava, Kenneth S. Kendler
openalex   +4 more sources

Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

open access: yesNature Communications, 2021
Major depressive disorder (MDD) has been shown to be associated with structural abnormalities in a variety of spatially diverse brain regions. However, the correlation between brain structural changes in MDD and gene expression is unclear.
Jiao Li   +10 more
semanticscholar   +1 more source

Associations between cardiac structure and function and depressive disorder: A centenarian study in China

open access: yesHeliyon, 2023
Background: Depressive disorder is a common comorbidity in patients with cardiovascular diseases and is associated with increased hospitalization and death rates.
Zhigao Sun   +7 more
doaj   +1 more source

Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications

open access: yesNeuroscience Bulletin, 2021
Major depressive disorder (MDD), also referred to as depression, is one of the most common psychiatric disorders with a high economic burden. The etiology of depression is still not clear, but it is generally believed that MDD is a multifactorial disease
Zezhi Li   +3 more
semanticscholar   +1 more source

Ethiopathogenesis of Depressive Disorders [PDF]

open access: yesClinical Practice & Epidemiology in Mental Health, 2014
Etiology of depressive disorders is still unknown. Several factors are involved in its pathophysiology such as neurotransmitters and neuroendocrine alterations, genetics, life events and their appraisal. Some of these components are strictly linked.
Pasquini, M., Berardelli, I., Biondi, M.
openaire   +4 more sources

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

open access: yesJAMA psychiatry, 2020
This randomized clinical trial examines the efficacy of psilocybin as an adjunct to psychotherapy and other treatments for major depressive disorder.
Alan K. Davis   +7 more
semanticscholar   +1 more source

Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2021
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As per the latest WHO report, MDD affects more than 260 million people worldwide.
Ajay Sarawagi, N. Soni, A. Patel
semanticscholar   +1 more source

Animal models for the study of depressive disorder

open access: yesCNS Neuroscience & Therapeutics, 2021
Depressive disorder is one of the most widespread forms of psychiatric pathology, worldwide. According to a report by the World Health Organization, the number of people with depression, globally, is increasing dramatically with each year.
Juhyun Song, Young-Kook Kim
semanticscholar   +1 more source

Inositol for depressive disorders [PDF]

open access: yesCochrane Database of Systematic Reviews, 2002
There are a number of effective interventions for the treatment of depression. It is possible that the efficacy of these treatments will be improved further by the use of adjunctive therapies such as inositol.1. To determine the effectiveness of inositol in the treatment of depression.2.
Taylor, M   +3 more
openaire   +3 more sources

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