Results 211 to 220 of about 3,696,874 (383)

The economic burden of adults with major depressive disorder in the United States (2005 and 2010).

Journal of Clinical Psychiatry, 2015
P. Greenberg, A. Fournier, Tammy Sisitsky, C. Pike, R. Kessler   +4 more
semanticscholar   +1 more source

H2O2‐Activated Serotonin Precursor Probe for Mapping Neuronal Redox Homeostasis Reveals 5‐HT Interactions with Neighboring Proteins Under Oxidative Stress

Advanced Science, EarlyView.
HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu, Jiwen Yuan, Tuanjie Zhang, Xinyi Cai, Meng Xu, Xueao Wang, Rui Wang, Bing Zhang, Hai‐Liang Zhu, Yong Qian   +9 more
wiley   +1 more source

PCN7: ECONOMIC ASPECTS OF AN INTERNATIONAL STUDY OF MAJOR DEPRESSIVE DISORDER IN PRIMARY CARE PATIENTS (THE LIDO STUDY)

, 1999
Daniel Chisholm, M Knapp, G. B. Simon, Michael Treglia   +3 more
openalex   +1 more source

P03.395 Therapy of depressive disorders with tianeptin and sertralin in patients with hypertension and ischemic heart disease [PDF]

, 2000
K. V. Tarasova, В. Краснов, Е. А. Нестерова, И. А. Садулаева, T. V. Dovzhenko   +4 more
openalex   +1 more source

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

Advanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao, Yi Wu, Haiyang Wang, Chenchun Zhang, Ying Zhu, Yan Jiang, Changyou Jiang, Qiumin Le, Xing Liu, Lan Ma, Feifei Wang   +10 more
wiley   +1 more source

WPA.01 The use of the WPA/PTD educational programme on the recognition and treatment of depressive disorders [PDF]

, 2000
Nikos C. Stefanis, J. E. Cooper, N. Kornetov   +2 more
openalex   +1 more source

Undertreatment of people with major depressive disorder in 21 countries

British Journal of Psychiatry, 2017
G. Thornicroft, S. Chatterji, S. Evans-Lacko, M. Gruber, N. Sampson, S. Aguilar-Gaxiola, A. Al-Hamzawi, J. Alonso, L. Andrade, G. Borges, R. Bruffaerts, B. Bunting, J. C. D. de Almeida, S. Florescu, G. de Girolamo, O. Gureje, J. Haro, Yan-ling He, H. Hinkov, E. Karam, N. Kawakami, Sing Lee, F. Navarro-Mateu, M. Piazza, J. Posada-Villa, Y. T. de Galvis, R. Kessler   +26 more
semanticscholar   +1 more source

Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top‐Down Middle Cingulate Amygdala Regulation and Brain‐Wide Fear Representations

Advanced Science, EarlyView.
This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu, Shuyue Xu, Zheng Zhang, Dan Liu, Ting Xu, Yuan Zhang, Feng Zhou, Xiaodong Zhang, Chunmei Lan, Junjie Wang, Lan Wang, Jingxian He, Keith M Kendrick, Bharat Biswal, Dezhong Yao, Zhen Liang, Weihua Zhao, Benjamin Becker   +17 more
wiley   +1 more source

P02.214 Therapeutic efficacy and metabolic peculiarities in patients with depressive disorders under tianeptine (TIA) and sertraline (SER) treatment [PDF]

, 2000
N. Maximova, E. Misionzhnik, О П Вертоградова, M. Usbekov   +3 more
openalex   +1 more source

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source