Results 111 to 120 of about 55,314 (289)
eLifeMetal-ion-dependent nucleases play crucial roles in cellular defense and biotechnological applications. Time-resolved crystallography has resolved catalytic details of metal-ion-dependent DNA hydrolysis and synthesis, uncovering the essential roles of ...
Caleb Chang, Grace Zhou, Yang Gao
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Carbon Acidity in Enzyme Active Sites
Frontiers in Bioengineering and Biotechnology, 2019 The pKa values for substrates acting as carbon acids (i.e., C-H deprotonation reactions) in several enzyme active sites are presented. The information needed to calculate them includes the pKa of the active site acid/base catalyst and the equilibrium ...
Michael D. Toney
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Experimental Investigation of Dynamic Deprotonation/Protonation of Highly Charged Particles [PDF]
, 2017 Single pores have found application in detecting and characterizing individual objects such as cells, particles, and even individual molecules. The experimental approach, called resistive-pulse technique, is often performed at symmetric electrolyte ...
Yinghua Qiu +5 more
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Advanced Science, EarlyView.We demonstrate how oxygen‐deficient ruthenium oxide (RuOx) nanoparticles confined within covalent organic framework achieve highly efficient nitrate‐to‐ammonia conversion. Strong interaction between RuOx nanoparticles and COF results in modified interfacial hydrogen‐bond water network and adsorption of nitrogenous intermediates.
Yun Li +6 more
wiley +1 more source
AntioxidantsThe principal reactions that maintain redox homeostasis in living systems are the deprotonation of thiols, followed by the oxidative conversion of the produced thiolates into disulfides, which thus reduce the harmful oxidizing agents.
Tamás Pálla +2 more
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Die Deprotonierung des Ni(II)-Aquoions (Stopped-Flow-Methode)
CHIMIA, 1971 A stopped flow procedure is described which allows to separate the deprotonation reaction of the Ni2+-aquoion from the formation of the polynuclear hydroxo species. The pK was determined to be 11,0.
H. Hohl, G. Geier
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Stepwise deprotonation of sumanene: electronic structures, energetics and aromaticity alterations [PDF]
, 2017 Stepwise deprotonation of sumanene resulted in complete delocalization of electron density as well as aromatization of 5-membered rings.
Qi Xu +2 more
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Advanced Science, EarlyView.We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang +13 more
wiley +1 more source
Regioselectivity of Pyridine Deprotonation in the Gas Phase [PDF]
, 2016 The regioselective deprotonation of pyridine in the gas phase has been investigated by using chemical reactivity studies. The mixture of regioisomers, trapped as carboxylates, formed in an equilibrium mixture is determined to result from 70−80 ...
Bonnie S. Schafman (2502022) +1 more
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Advanced Science, EarlyView.This work designs a peptide‐free polyelectrolyte with stable, switchable conformations and near‐infrared fluorescence in water. It harnesses a cooperative Fe3+‐triggered sheet‐to‐helix transition to generate nonlinear fluorescence quenching, enabling the ultrasensitive, real‐time visualization of Fe3+ ion distribution and metabolic trafficking at ...
Yeqiang Zhou +9 more
wiley +1 more source