Results 41 to 50 of about 374 (147)

Hepatoprotective activity of depsidone enriched Cladonia rangiferina extract against alcohol-induced hepatotoxicity targeting cytochrome P450 2E1 induced oxidative damage

Saudi Pharmaceutical Journal, 2020
Alcoholic liver disease (ALD) is a broad-spectrum disorder, covering fatty liver, cirrhosis, alcoholic hepatitis and in extreme untreated condition hepatocellular carcinoma (HCC) may also develop.
Ila Shukla, Lubna Azmi, Ch. V. Rao, Talha Jawaid, Mehnaz Kamal, Amani S. Awaad, Saleh I. Alqasoumi, Osama A. Alkhamees, Saud M. Alsanad   +8 more
doaj   +1 more source

Effectiveness and Anticancer Activity of a Novel Phenolic Compound from Garcinia porrecta Against the MCF-7 Breast Cancer Cell Line in vitro and in silico

Drug Design, Development and Therapy, 2021
Darwati Darwati, Ayu Nadila Safitri, Nurul Ambardhani, Tri Mayanti, Nurlelasari Nurlelasari, Dikdik Kurnia Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, West Java ...
Darwati D, Safitri AN, Ambardhani N, Mayanti T, Nurlelasari N, Kurnia D   +5 more
doaj  

Dereplicative Combination of HPLC/DAD/MS and 2D NMR to Identify Lichexanthone Isomers in Lichen Extracts

Phytochemical Analysis, Volume 37, Issue 2, Page 330-343, March 2026.
ABSTRACT Introduction Lichexanthones are the major xanthones found in lichens. They present a high degree of isomerism, which makes their identification tedious. Xanthones are known to occur in lichens according to chemosyndromes, and these compounds act as chemotaxonomic markers.
Solenn Ferron, Marylène Chollet‐Krugler, Hermann Pinson, Rania Marzoug, Philippe Uriac, Françoise Lohézic‐Le Dévéhat   +5 more
wiley   +1 more source

Functional Traits Mediate Physico‐Chemical Niche Differentiation of Epiphytic Lichens and Bryophytes in Temperate Forests

Journal of Vegetation Science, Volume 37, Issue 2, March/April 2026.
Host tree identity drives bark physico‐chemical filters (e.g., pH, metals) that shape epiphytic communities. We show that species‐specific functional traits, such as lichen substances and bryophyte growth forms, mediate these responses. Lichen metal homeostasis and bryophyte growth habit create distinct species thresholds and community change points ...
Theresa Möller, Stefan Kaufmann, Markus Hauck   +2 more
wiley   +1 more source

Bioproduction of Depsidones for Pharmaceutical Purposes

, 2011
الأشنات هي تكافلات حميمة وطويلة الأجل محددة من الطحالب الضوئية أو البكتيريا الزرقاء والفطريات غيرية التغذية التي انضمت لتشكيل كيان بيولوجي جديد مختلف عن مكوناته الفردية (جالون وكارديش، 1995). ينتج الكلوروليكين بشكل أساسي مواد فينولية فريدة من نوعها، ديبيد، ديبسيدون وبعض ثنائي بنزوفيوران، مثل أحماض اليوزنيك (Huneck & Yoshimura، 1996)، التي لا تنتجها ...
Maria Estrella, Roberto de, Carlos Vicente   +2 more
openaire   +2 more sources

Lobaric Acid Exhibits Anticancer Potential by Modulating the Wnt/β‐Catenin Signaling Pathway in MCF‐7 Cells

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
Effect of lobaric acid on Wnt/β‐catenin pathway in breast cancer. ABSTRACT Lichen secondary metabolites with many remarkable biological activities are used in cancer treatments due to their low side effects and high anticancer potential. In particular, these metabolites constitute an interesting research area in cancer treatments due to their potential
Şeyda Nur Kalın, Kübra Nur Bayındırlı, Emine Toraman, Şükran Günaydın, Fatmanur Keleş, Ahmet Altay, Harun Budak   +6 more
wiley   +1 more source

Lichen and Its Microbiome as an Untapped Source of Anti‐Biofilm Compounds

Chemistry &Biodiversity, Volume 22, Issue 4, April 17, 2025.
Lichens and their associated fungi give rise to the evaluation of several extracts and compounds against biofilms. ABSTRACT Lichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized. Most of them have been evaluated for their activity on planktonic microorganisms (bacteria and fungi ...
Marion Millot, Christine Imbert, Christelle Pouget, Marion Girardot, Lengo Mambu   +4 more
wiley   +1 more source

Conventional and innovative approaches to black fungi control for stone heritage preservation

IUBMB Life, Volume 77, Issue 3, March 2025.
Abstract Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups of microorganisms causing the deterioration of outdoor exposed stone monuments mainly due to the formation of dark spots and patches leading to the darkening of their surface ...
Domenico Celi, Massimiliano Marvasi, Brunella Perito   +2 more
wiley   +1 more source

Biosynthesis of Depsides, Depsidones, and Diphenyl Ethers from Fungi and Lichens

Asian Journal of Organic Chemistry, Volume 14, Issue 2, February 2025.
Depsides are natural products derived from (poly)phenolic acid derivatives connected by ester bonds. Recent research has revealed crucial molecular mechanisms and distinctive enzymatic chemistry underlying the biosynthesis of depsides, as well as related natural products, such as depsidones and diphenyl ethers.
Qiaolin Ji, Yudai Matsuda
wiley   +1 more source

Spiromastixones Inhibit Foam Cell Formation via Regulation of Cholesterol Efflux and Uptake in RAW264.7 Macrophages

Marine Drugs, 2015
Bioassay-guided evaluation shows that a deep sea-derived fungus, Spiromastix sp. MCCC 3A00308, possesses lipid-lowering activity. Chromatographic separation of a culture broth resulted in the isolation of 15 known depsidone-based analogues, labeled ...
Chongming Wu, Ran Chen, Mingyue Liu, Dong Liu, Xin Li, Shuai Wang, Siwen Niu, Peng Guo, Wenhan Lin   +8 more
doaj   +1 more source