Results 71 to 80 of about 7,087,724 (289)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Shape representations in the primate dorsal visual stream

Frontiers in Computational Neuroscience, 2015
The primate visual system extracts object shape information for object recognition in the ventral visual stream. Recent research has demonstrated that object shape is also processed in the dorsal visual stream, which is specialized for spatial vision and
Tom eTheys, Tom eTheys, Maria C. Romero, Johannes evan Loon, Peter eJanssen   +4 more
doaj   +1 more source

Determination of the Depth Scale in Sputter Depth Profiling

Journal of Surface Analysis, 2002
One of the fundamental parameters in quantification of sputter depth profiles is the sputtered depth. Usually, the sputtered depth is not known from the measured profile, because only the sputtering time is recorded. Only if the instantaneous sputtering rate (=sputtered depth per unit of time) is known, the depth scale can be derived from the time ...
Hofmann, S., Wang, J.
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Development of a severe rat refeeding syndrome model and mathematical modeling of the associated hypophosphatemia

npj Systems Biology and Applications
Refeeding syndrome (RFS) is a life-threatening metabolic complication caused by refeeding in malnourished patients and is a barrier to early nutritional supplementation.
Hiroaki Kato, Ippei Yamaoka, Hiroyuki Kubota   +2 more
doaj   +1 more source

Depth Jitter: Seeing Through the Depth

OCEANS 2025 - Great Lakes
Depth information is essential in computer vision, particularly in underwater imaging, robotics, and autonomous navigation. However, conventional augmentation techniques overlook depth aware transformations, limiting model robustness in real world depth variations.
Rahman, Md Sazidur, Cabecinhas, David, Marxer, Ricard   +2 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Plant chloroplast stress response: insights from mass spectrometry metabolites analysis

Frontiers in Plant Science
Plant chloroplasts produce excess reactive oxygen species (ROS) during photosynthesis, particularly under biotic and abiotic stress conditions.
Si Cheng, Si Cheng, Jiawei Xu, Jiawei Xu, Siqi Wu, Qun Li, Jianing Mi, Jianing Mi   +7 more
doaj   +1 more source

Comparative Performance Analysis of Novel Single-Slope Conventional Solar Still and Solar Still with ZnO Water Nanofluids through Experimental Investigation [PDF]

E3S Web of Conferences
Aim: This research primary aim is to explore efficiency of utilizing ZnO nanoparticles in elevating the solar still productivity for purifying saltwater into freshwater.
Sailash N., Sakthivel T.G.
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source