Results 71 to 80 of about 3,776,208 (307)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Visual discomfort and depth-of-field [PDF]
, 2013 This research was part funded by the BBSRC and EPSRC.Visual discomfort has been reported for certain visual stimuli and under particular viewing conditions, such as stereoscopic viewing.
Zhang, T. +21 more
core +2 more sources
Shape representations in the primate dorsal visual stream
Frontiers in Computational Neuroscience, 2015 The primate visual system extracts object shape information for object recognition in the ventral visual stream. Recent research has demonstrated that object shape is also processed in the dorsal visual stream, which is specialized for spatial vision and
Tom eTheys +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
npj Systems Biology and ApplicationsRefeeding syndrome (RFS) is a life-threatening metabolic complication caused by refeeding in malnourished patients and is a barrier to early nutritional supplementation.
Hiroaki Kato +2 more
doaj +1 more source
Plant chloroplast stress response: insights from mass spectrometry metabolites analysis
Frontiers in Plant SciencePlant chloroplasts produce excess reactive oxygen species (ROS) during photosynthesis, particularly under biotic and abiotic stress conditions.
Si Cheng +7 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Depth-based inference for functional data [PDF]
, 2006 We propose robust inference tools for functional data based on the notion of depth for curves. We extend the ideas of trimmed regions, contours and central regions to functions and study their structural properties and asymptotic behavior.
Romo, Juan +3 more
core +1 more source
Comparative Performance Analysis of Novel Single-Slope Conventional Solar Still and Solar Still with ZnO Water Nanofluids through Experimental Investigation [PDF]
E3S Web of ConferencesAim: This research primary aim is to explore efficiency of utilizing ZnO nanoparticles in elevating the solar still productivity for purifying saltwater into freshwater.
Sailash N., Sakthivel T.G.
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source