Results 71 to 80 of about 4,496,548 (308)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

DEPTH MAP ESTIMATION IN LIGHT FIELDS USING AN STEREO-LIKE TAXONOMY

open access: yesRevista de Investigaciones Universidad del Quindío, 2016
The light field or LF is a function that describes the amount of light traveling in every direction (angular) through every point (spatial) in a scene, this LF can be captured in several ways, using arrays of cameras, or more recently using a single ...
Francisco C. Calderon   +2 more
doaj   +1 more source

Guided Depth Map Super-Resolution Using Recumbent Y Network

open access: yesIEEE Access, 2020
Low spatial resolution is a well-known problem for depth maps captured by low-cost consumer depth cameras. Depth map super-resolution (SR) can be used to enhance the resolution and improve the quality of depth maps.
Tao Li, Xiucheng Dong, Hongwei Lin
doaj   +1 more source

Polarization distributed depth map for depth-fused three-dimensional display

open access: yesOptics Express, 2011
We propose a polarization distributed depth map (PDDM) which can be used in a depth-fused three-dimensional (DFD) display. PDDM is obtained from a conventional depth map using a polarization switching device and shows different polarization states for each pixel depending on the depth position of corresponding pixel.
Soon-gi, Park   +2 more
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Nonlinear Depth Map Resampling for Depth-Enhanced 3-D Video Coding

open access: yesIEEE Signal Processing Letters, 2013
Depth-enhanced 3-D video coding includes coding of texture views and associated depth maps. It has been observed that coding of depth map at reduced resolution provides better rate-distortion performance on synthesized views comparing to utilization of full resolution (FR) depth maps in many coding scenarios based on the Advanced Video Coding (H.264 ...
Aflaki, Payman   +3 more
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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