Results 81 to 90 of about 167,827,407 (289)

A Study of Optimization of Machining Conditions in Micro End-Milling By Using Response Surface Design

open access: yesInternational Journal of Technology, 2014
In cases of end-milling removal rate, depth of cut, cutting velocity and feedrate were taken into account as important factors affecting machining quality, tool fracture, tool wear and so on.
Tae-Il Seo   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Comparative Study on the Effect of Tool Wear on Turning Mild Steel and Stainless Steel with a Ceramic Tool Insert Using Taguchi Method

open access: yesEngineering Proceedings
Machining is a critical aspect of metalworking since it is used to cut metal. Machine tools, particularly cutting tools, are critical in metalworking for successful metal cutting.
S. Raghu   +5 more
doaj   +1 more source

Investigation on Depth of Cut by Varying Cutting Parameters for Single Pass Cutting On CO2 Laser

open access: yesInternational Journal of Innovative Research in Science, Engineering and Technology, 2014
Emergence of advanced engineering materials, stringent design requirements, intricate shape and unusual size of workpiece restrict the use of conventional machining methods. Laser Beam Machining (LBM) is one of the advance manufacturing processes which are used for shaping almost whole range of engineering materials.
A A Shaikh, A M Varsi
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Statistical analysis of the effect of machining parameters on the straightness error of high carbon steel turned components

open access: yesمجلة المختار للعلوم, 2013
The objective of the present work is to study the effect of machining parameters on the straightness error of cylindrical parts of high carbon steel (SAE 1095) having hardness 210 BH produced in a lathe machine.
Abdulmansaf A Bouzaid   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Multivariate risks and depth-trimmed regions [PDF]

open access: yes, 2006
Acceptance set, Cone, Depth-trimmed region, Multivariate risk, Risk measure, 91B30, 91B82, 60D05, 62H99, C60, C61,
Molchanov, Ilya   +4 more
core   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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