Results 61 to 70 of about 320,019 (256)
Investigation on the Impact Fracture Mechanism of Rock in Microgravity Environment Using the Continuum-Discontinuum Element Method [PDF]
LithosphereIn-depth analysis of asteroid samples will provide a key scientific basis for understanding its evolution history, resource utilization, and life origin. Obtaining rock samples from asteroids is getting more and more attention.
Qunlei Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
International Journal of Technology, 2014 In cases of end-milling removal rate, depth of cut, cutting velocity and feedrate were taken into account as important factors affecting machining quality, tool fracture, tool wear and so on.
Tae-Il Seo +4 more
doaj +1 more source
On Minimum Depth of Cut in nanomachining [PDF]
, 2010 The concept of Minimum Depth of Cut (MDC) is that the depth of cut must be over a certain critical thickness before any chip is formed. It is actually a major limiting factor on achievable accuracy in nanomachining, because the generated surface roughness is primarily attributed to the ploughing process when the uncut chip thickness is less than the ...
Oluwajobi, Akinjide O., Chen, Xun
openaire
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Engineering ProceedingsMachining is a critical aspect of metalworking since it is used to cut metal. Machine tools, particularly cutting tools, are critical in metalworking for successful metal cutting.
S. Raghu +5 more
doaj +1 more source
Investigation on Depth of Cut by Varying Cutting Parameters for Single Pass Cutting On CO2 Laser
International Journal of Innovative Research in Science, Engineering and Technology, 2014 Emergence of advanced engineering materials, stringent design requirements, intricate shape and unusual size of workpiece restrict the use of conventional machining methods. Laser Beam Machining (LBM) is one of the advance manufacturing processes which are used for shaping almost whole range of engineering materials.
A A Shaikh, A M Varsi
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
مجلة المختار للعلوم, 2013 The objective of the present work is to study the effect of machining parameters on the straightness error of cylindrical parts of high carbon steel (SAE 1095) having hardness 210 BH produced in a lathe machine.
Abdulmansaf A Bouzaid +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source