Results 51 to 60 of about 758,450 (252)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Calculation and Analysis of Key Parameters of Underwater Optical Imaging System

open access: yesSensors
When photographing objects underwater, it is important to utilize an optical window to isolate the imaging device from the water. The properties of the entire imaging system will change, and the imaging quality will decrease due to the refraction impact ...
Guangpeng Zhou   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Depth-sensing technology using a negative microlens array

open access: yesInternational Journal of Optomechatronics, 2021
In this study, an optical depth-sensing system whose focus distance was equal to its object distance was constructed by using a lens with a shortened depth of field.
Chih-Hsiung Lin, Kun-Huang Chen
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Visual outcomes and spectacle independence of a non-diffractive wavefront-shaping intraocular lens in post-LASIK patients

open access: yesFrontiers in Medicine
PurposeTo compare visual outcomes, depth of field (DOF), spectacle independence, and patient satisfaction of cataract patients with and without previous myopic laser in situ keratomileusis (LASIK) surgery who received a non-diffractive extended range-of ...
Wei Fan   +17 more
doaj   +1 more source

Dual-Element Transducer with Phase-Inversion for Wide Depth of Field in High-Frequency Ultrasound Imaging

open access: yesSensors, 2014
In high frequency ultrasound imaging (HFUI), the quality of focusing is deeply related to the length of the depth of field (DOF). In this paper, a phase-inversion technique implemented by a dual-element transducer is proposed to enlarge the DOF.
Jong Seob Jeong
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

EyeAR: Refocusable Augmented Reality Content through Eye Measurements

open access: yesMultimodal Technologies and Interaction, 2017
Augmented Reality (AR) superimposes computer graphics (CG) onto a user’s view of the real world. A key quality problem in this field is to achieve coherence between reality and CG when the user’s eyes refocus or change pupil size.
Damien Constantine Rompapas   +7 more
doaj   +1 more source

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