Results 151 to 160 of about 97,672 (267)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

[Requirements for the rational use of antibiotics based on antibiotic stewardship]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
de With K, Draenert R, Nurjadi D, Hagel S, Trost U, Fahrenkrog-Petersen J, Kern WV, Kramme E.   +7 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

A neuropsychological perspective on sensory hypersensitivity after acquired brain injury. [PDF]

Brain Commun
Heijman JO, Marzolla MC, Thielen H, Spielmann K, Königs M, Gillebert CR, van Heugten CM, van der Stoep N, Huenges Wajer IMC.   +8 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

[Autism spectrum disorders-Transition from adolescence into adulthood]. [PDF]

Nervenarzt
Freitag CM, Tebartz van Elst L.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A multi‑country evaluation of healthcare professionals' experiences with the PanCareFollowUp training package to implement person-centred care in childhood cancer survivorship care: A PanCareFollowUp study. [PDF]

Support Care Cancer
Loonen JJ, Bouwman E, Penson A, Follin C, Uyttebroeck A, Breij D, Kepakova K, Prikken S, Hjorth L, Winther JF, van der Pal HJH, Schneider C, Kienesberger A, Gsell H, Michel G, Pluijm SMF, Skinner R, Kremer LCM, Muraca M, Kepak T, Hermens RPMG, PanCareFollowUp Consortium.   +21 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

2D Nanomaterials Toward Function-Ready Superlubricity in Advanced Microsystems. [PDF]

Adv Mater
Geng Y, Yang J, Yang Y.
europepmc   +1 more source