Results 121 to 130 of about 10,956,350 (300)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Integration of DER & RES in Power System and Distribution Network Design
The European Integrated Project EU-DEEP, which deals with the integration of Distributed Energy Resources in the transmission and distribution system, proposes technical, operational and regulatory analyses, developed in a coordinated way, as the best ...
Deuse, J. +3 more
core
Das Universitätsmagazin berichtet über die vielfältigen Aktivitäten der Universität in Forschung, Studium und Universitätskliniken, informiert über Tiergesundheit, Tierhaltung und Tierschutz sowie Lebensmittelsicherheit und beschäftigt sich mit Fragen ...
Gesellschaft der Freunde der Veterinärmedizinischen Universität Wien +1 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Metamorphosen der regionalen Integration [PDF]
openaire +3 more sources
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Integration der Flexibilitätsvermarktung
Die Energiesynchronisationsplattform adressiert den gesamten Prozess des automatisierten Energieflexibilitätshandels von der Maschine bis zu den Vermarktungsservices. Sie stellt somit das übergeordnete Gesamtkonzept eines digitalen Ökosystems dar, welches industrielle Nachfrageflexibilität ermöglicht. Die Energiesynchronisationsplattform besteht dabei
Ahrens, Raphael +22 more
openaire +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

