Results 151 to 160 of about 20,039,291 (337)
Der kommunikativ-produktive Charakter des kollektiven Gedächtnisses basiert auf einem Ausschluss von "beschämender" Vergangenheit. Für HABERMAS besteht der Kampf um einen kommunikativen Raum in der Abgrenzung zwischen Wirtschafts- und Herrschaftsmacht ...
Magdalena Nowicka
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Der integrative Prozess in der Psychotherapie: Methodenvielfalt - Synergismus, Integration
openaire +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
[Training and clinical use of focused echocardiography : Evaluation of the state of training and clinical application of perioperative focused echocardiography by anesthesiologists in Germany]. [PDF]
Kummerow T +6 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The linguistic and educational integration of children and adolescents from migrant backgrounds
Die Integration von Migranten und Migrantinnen in den Aufnahmeländern, ist für den sozialen Zusammenhalt von fundamentaler Bedeutung und daher ein zentrales Anliegen des Europarats.
David Little
doaj
Digital Pathology in Dermatology - Current Status, Applications and Perspectives. [PDF]
Müller CSL, Hansen T.
europepmc +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

