Results 121 to 130 of about 20,039,291 (337)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2009 Das VUW Magazin war das Universitätsmagazin der Veterinärmedizinischen Universität Wien (Vetmeduni) und wurde vom Vetmed Magazin abgelöst. Es wurde gemeinsam mit der Gesellschaft der Freunde der Veterinärmedizinischen Universität Wien herausgegeben ...
Gesellschaft der Freunde der Veterinärmedizinischen Universität Wien +1 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Integration of DER & RES in Power System and Distribution Network Design
The European Integrated Project EU-DEEP, which deals with the integration of Distributed Energy Resources in the transmission and distribution system, proposes technical, operational and regulatory analyses, developed in a coordinated way, as the best ...
Deuse, J. +3 more
core
, 2020 Das Universitätsmagazin berichtet über die vielfältigen Aktivitäten der Universität in Forschung, Studium und Universitätskliniken, informiert über Tiergesundheit, Tierhaltung und Tierschutz sowie Lebensmittelsicherheit und beschäftigt sich mit Fragen ...
Gesellschaft der Freunde der Veterinärmedizinischen Universität Wien +1 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Metamorphosen der regionalen Integration [PDF]
Journal für Entwicklungspolitik, 2006 openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Menschliche Existenz, (Nicht)Nachhaltigkeit & Künstliche Intelligenz
MedienimpulseDer Beitrag untersucht die komplexen Zusammenhänge zwischen Künstlicher Intelligenz (KI), Alignment und Nachhaltigkeit und beleuchtet deren Bedeutung für zukünftige gesellschaftliche Transformationsprozesse.
Daniel Autenrieth, Jan-René Schluchter
doaj +1 more source