Results 81 to 90 of about 101,704 (267)

Concepts for cultural integration after M&A

Business: Theory and Practice, 2011
When integrating corporate cultures after Mergers & Acquisitions (M&A) the conceptual approach is of central importance. This integrated approach should be selected before the actual integration takes place.
Andreas Palm
doaj  

Sprachunterricht als Transformationsraum

DiSlaw
Trotz der zunehmenden Wichtigkeit der Bildung für nachhaltige Entwicklung (BNE) in bildungspolitischen Kontexten bleibt ihre Integration in Sprachkurse auf Hochschulniveau begrenzt.
Natalia Schwarzl
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Metamorphosen der regionalen Integration [PDF]

Journal für Entwicklungspolitik, 2006
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Integration der Flexibilitätsvermarktung

, 2022
Die Energiesynchronisationsplattform adressiert den gesamten Prozess des automatisierten Energieflexibilitätshandels von der Maschine bis zu den Vermarktungsservices. Sie stellt somit das übergeordnete Gesamtkonzept eines digitalen Ökosystems dar, welches industrielle Nachfrageflexibilität ermöglicht. Die Energiesynchronisationsplattform besteht dabei
Ahrens, Raphael, Köberlein, Jana, Bank, Lukas, Kalchschmid, Vincent, Oeder, Andreas, Schlereth, Andreas, Grigorjan, Arthur, Kaymakci, Can, Schel, Daniel, Bauer, Dennis, Schulz, Fabian, Lodwig, Ragnar, Bauernhansl, Thomas, Sauer, Alexander, Lindner, Martin, Weigold, Matthias, Schulz, Julia, SCHOEPF, Michael, VAN STIPHOUDT, Christine, FRIDGEN, Gilbert, POTENCIANO MENCI, Sergio, Winter, Christian, Schimmelpfennig, Jens   +22 more
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source