Results 51 to 60 of about 437,480 (390)
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Taxi Violence in South Africa: A Review of Literature and Critical Analysis [PDF]
Journal of Education and Learning TechnologyThe taxi industry plays an important role in society by transporting commuters from point A to point B daily. This industry contributes to the economic growth of South Africa. However, it is faced with challenges of violence where taxi associations fight
Mmakwena Modipa
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Conflits et négociations au Havre avant et après les grandes réformes portuaires
L'Espace Politique, 2012 Contrary to what many observers expected, the two main port reforms implemented in Le Havre (1992 and 2008), far from reducing the numbers and combative spirit of the Le Havre dockers' union, have strengthened it.
John Barzman
doaj +1 more source
Labor Market Outcomes of Deregulation in Telecommunications Services [PDF]
, 1998 [Excerpt] This paper examines the labor market outcomes of deregulation in the telecommunications industry, focusing specifically on changes in union density, real wages, wage inequality, and employment levels.
Batt, Rosemary, Strausser, Michael
core +2 more sources
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Précaires sur les pistes aéroportuaires
La Nouvelle Revue du Travail, 2016 European airline deregulation policies have led to greater outsourcing of ground handling services and caused in turn a casualisation of labour. Facing the segmentation of work groups and given the uncertainty that accompanies flexible work, management ...
Fabien Brugière
doaj +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Energies, 2020 In the work reported in this paper, a novel application of the artificial bee colony algorithm is used to implement a virtual inertia control strategy for grid-connected wind energy conversion systems.
Anuoluwapo Oluwatobiloba Aluko +3 more
doaj +1 more source