Results 121 to 130 of about 13,781 (277)

Long‐read sequencing for biodiversity analyses—A comprehensive guide

Methods in Ecology and Evolution, Volume 17, Issue 3, Page 650-667, March 2026.
Abstract DNA‐based monitoring of biodiversity has revolutionised our ability to describe communities and rapidly assess anthropogenic impacts on biodiversity. Currently established molecular methods for biomonitoring rely heavily on classic metabarcoding utilising short reads, mostly through Illumina data.
Iliana Bista, Alexandra Lino
wiley   +1 more source

Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy. [PDF]

, 2017
In mass spectrometry-based untargeted metabolomics, rarely more than 30% of the compounds are identified. Without the true identity of these molecules it is impossible to draw conclusions about the biological mechanisms, pathway relationships and ...
Biedendieck, Rebekka, Blaženović, Ivana, Fiehn, Oliver, Jahn, Dieter, Jahn, Martina, Kind, Tobias, Mehta, Sajjan S, Obrenović, Slobodan, Schauer, Nicolas, Torbašinović, Hrvoje, Tsugawa, Hiroshi, Wermuth, Tobias   +11 more
core   +2 more sources

Influence of OSMAC-Based Cultivation in Metabolome and Anticancer Activity of Fungi Associated with the Brown Alga Fucus vesiculosus

Marine Drugs, 2019
The fungi associated with marine algae are prolific sources of metabolites with high chemical diversity and bioactivity. In this study, we investigated culture-dependent fungal communities associated with the Baltic seaweed Fucus vesiculosus. Altogether,
Bicheng Fan, Delphine Parrot, Martina Blümel, Antje Labes, Deniz Tasdemir   +4 more
doaj   +1 more source

Freshwater and Sediment Host Distinct Yet Overlapping Microeukaryotic Communities, With Sediment Communities Less Impacted by Treated Wastewater

Journal of Eukaryotic Microbiology, Volume 73, Issue 2, March/April 2026.
ABSTRACT Freshwater and sediment environments host diverse microeukaryotic communities that differ in structure and composition, yet exhibit taxonomic overlap. Using 18S V9 rRNA gene sequencing, we compared communities from these habitats in controlled 10‐day mesocosm experiments, examining diversity, overlap, and responses to treated wastewater (TWW).
Radtke Kim, Bludau Dana, Boenigk Jens, Sieber Guido   +3 more
wiley   +1 more source

Black perithecial pigmentation in Fusarium species is due to the accumulation of 5-deoxybostrycoidin-based melanin [PDF]

, 2016
Biosynthesis of the black perithecial pigment in the filamentous fungus Fusarium graminearum is dependent on the polyketide synthase PGL1 (oPKS3). A seven-membered PGL1 gene cluster was identified by over-expression of the cluster specific transcription ...
Frandsen, Rasmus John Normand, Giese, Henriette, Gotfredsen, Charlotte Held, Knudsen, Peter Boldsen, Larsen, Thomas Ostenfeld, Lysøe, Erik, Petersen, Dirk, Rasmussen, Silas Anselm, Uhlig, Silvio   +8 more
core   +1 more source

Chemical Profiling (HPLC-NMR & HPLC-MS), Isolation, and Identification of Bioactive Meroditerpenoids from the Southern Australian Marine Brown Alga Sargassum paradoxum

Marine Drugs, 2014
A phytochemical investigation of a southern Australian marine brown alga, Sargassum paradoxum, resulted in the isolation and identification of four new (5, 9, 10, and 15) and nine previously reported (1, 2, 6–8, and 11–14) bioactive meroditerpenoids ...
Robert Brkljača, Sylvia Urban
doaj   +1 more source

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Individuals with similar white matter hyperintensities (WMH) burden show heterogeneous cognitive outcomes, yet the biological mechanisms underlying this variability remain incompletely understood. METHODS We integrated 16S rDNA sequencing, untargeted metabolomics, and multi‐modal magnetic resonance imaging (MRI) to comprehensively
Xiaotao Xu, Xia Zhou, Mengwei Zhang, Jingjing Fang, Zhiqing Yan, Xiaoqun Zhu, Yongqiang Yu, Jiajia Zhu   +7 more
wiley   +1 more source

Dereplication Guided Discovery of Secondary Metabolites of Mixed Biosynthetic Origin from Aspergillus aculeatus [PDF]

, 2014
Investigation of the chemical profile of the industrially important black filamentous fungus Aspergillus aculeatus by UHPLC-DAD-HRMS and subsequent dereplication has led to the discovery of several novel compounds.
Frisvad, Jens Christian, Gotfredsen, Charlotte Held, Hoeck, Casper, Larsen, Thomas Ostenfeld, Petersen, Lene Maj   +4 more
core   +2 more sources

Identification of Antioxidant, Antimicrobial, and Cytotoxic Compounds From Hymenocardia acida Tul. Using Ultra‐High‐Performance Liquid Chromatography‐Quadrupole Exactive‐Orbitrap‐Mass Spectrometry and Molecular Networking Approach

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Hymenocardia acida Tul. is a medicinal plant used in Angola to treat microbial diseases. It is a well‐known plant among local populations; however, few studies have focused on the assessment of phytochemicals associated with their biological activities.
Ntsoaki Joyce Malebo, Idah Tichaidza Manduna, Monizi Mawunu, Ramakwala Christinah Chokwe, Bafedile Tlhapi   +4 more
wiley   +1 more source

Physiological characterization of secondary metabolite producing Penicillium cell factories [PDF]

, 2017
Background Penicillium species are important producers of bioactive secondary metabolites. However, the immense diversity of the fungal kingdom is only scarcely represented in industrial bioprocesses and the upscaling of compound production remains a ...
Frandsen, Rasmus John Normand, Frisvad, Jens Christian, Grijseels, Sietske, Larsen, Thomas Ostenfeld, Nielsen, Jens, Nielsen, Jens, Nielsen, Kristian Fog, Workman, Mhairi   +7 more
core   +2 more sources