Results 131 to 140 of about 13,781 (277)
Molecules, 2015 Nucleobase and nucleoside compounds exist widely in various organisms. An often occurring problem in the discovery of new bioactive compounds from natural products is reisolation of known nucleobase and nucleoside compounds.
Junhui Chen +4 more
doaj +1 more source
Linking Metabolomic Diversity to Pharmacological Potency in Anonidium mannii Leaf Extracts
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.This study investigates the metabolomic profile and pharmacological activities of extracts from Anonidium mannii leaves. The extracts were profiled using an integrated LC‐MS/GC‐MS, and evaluated for antimicrobial, antioxidant and cytotoxic activities, providing a basis for future studies and validation in more advanced biological models.
Olusesan Ojo +2 more
wiley +1 more source
New Antiproliferative Cembrane Diterpenes from the Red Sea Sarcophyton Species
Marine Drugs, 2019 The combination of liquid chromatography coupled to high resolution mass spectrometry (LC-HRESMS)-based dereplication and antiproliferative activity-guided fractionation was applied on the Red Sea-derived soft coral Sarcophyton sp.
Hossam M. Hassan +11 more
doaj +1 more source
An Integrated Metabolomic and Genomic Mining Workflow to Uncover the Biosynthetic Potential of Bacteria [PDF]
, 2016 Microorganisms are a rich source of bioactives; however, chemical identification is a major bottleneck. Strategies that can prioritize the most prolific microbial strains and novel compounds are of great interest.
Andreas Klitgaard +11 more
core +2 more sources
Frontiers in Molecular Biosciences, 2016 Dereplication based on hyphenated techniques has been extensively applied in plant metabolomics, avoiding re-isolation of known natural products. However, due to the complex nature of biological samples and their large concentration range, dereplication ...
Fausto Carnevale Neto +9 more
doaj +1 more source
Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]
, 2019 Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing +3 more
core +1 more source
Desreplicação de alcaloides aporfínicos e oxoaporfínicos de Unonopsis guatterioides por ESI-IT-MS
Química Nova, 2012 The dereplication of aporphine and oxoaporphine alkaloids by direct infusion in ESI-IT-MSn system was applied for alkaloidal fractions of the Unonopsis guatterioides (Annonaceae).
Felipe Moura Araújo da Silva +5 more
doaj +1 more source