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Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones
Bioorganic Chemistry, 2019Previous study demonstrated large scale production of trichochecenes which limited the discovery of novel metabolites in Trichoderma hypoxylon. By genetic deletion of trichothecene synthase encoding gene thtri5, we created the dereplication mutant which eliminated the production of trichothecenes.
Lin, Chen +7 more
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The dereplication of plant-derived natural products
1996Publisher Summary The dereplication of natural products is gaining greater importance in optimizing the process of natural product drug discovery as the pace of evaluating natural product extracts for their biological potential has increased. Over the years, as new technologies are introduced into analytical chemistry, they have been applied to ...
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Strategies for Database Dereplication of Natural Products
Journal of Natural Products, 1994David G. Corley, Richard C. Durley
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Dereplication and Chemotyping in Marine Samples
2004Dieckmann, Ralf, Döhren, Hans Von
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Advances in Instrumentation, Automation, Dereplication and Prefractionation
2009Tim S. Bugni* +3 more
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Dereplication and Partial Identification of Natural Products
1998Frank Van Middlesworth +1 more
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