Results 21 to 30 of about 13,781 (277)
Recovery of genomes from metagenomes via a dereplication, aggregation and scoring strategy [PDF]
Nature Microbiology, 2018 Microbial communities are critical to ecosystem function. A key objective of metagenomic studies is to analyse organism-specific metabolic pathways and reconstruct community interaction networks.
Christian M. K. Sieber +6 more
openalex +2 more sources
MALDI-TOF MS: application in diagnosis, dereplication, biomolecule profiling and microbial ecology [PDF]
Proceedings of Indian National Science Academy, 2022 Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized scientific research over the past few decades and has provided a unique platform in ongoing technological developments.
Najeebul Tarfeen +2 more
openalex +2 more sources
13C NMR Dereplication Using MixONat Software: A Practical Guide to Decipher Natural Products Mixtures [PDF]
Planta Medica, 2021 The growing use of herbal medicines worldwide requires ensuring their quality, safety, and efficiency to consumers and patients. Quality controls of vegetal extracts are usually undertaken according to pharmacopeial monographs.
Antoine Bruguière +5 more
openalex +2 more sources
skDER and CiDDER: two scalable approaches for microbial genome dereplication. [PDF]
Microb GenomAn abundance of microbial genomes have been sequenced in the past two decades. For fundamental comparative genomic investigations, where the goal is to determine the major gain and loss events shaping the pangenome of a species or broader taxon, it is ...
Salamzade R, Kottapalli A, Kalan LR.
europepmc +2 more sources
Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. [PDF]
, 2018 The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured elucidation approaches and software that are designed to help during the annotation of unknown compounds.
Blaženović, Ivana +3 more
core +7 more sources
Molecules, 2021 The role and importance of the identification of natural products are discussed in the perspective of the study of secondary metabolites. The rapid identification of already reported compounds, or structural dereplication, is recognized as a key element ...
Mariacaterina Lianza +8 more
doaj +1 more source
To Dereplicate or Not To Dereplicate? [PDF]
mSphere, 2019 Metagenome-assembled genomes (MAGs) expand our understanding of microbial diversity, evolution, and ecology. Concerns have been raised on how sequencing, assembly, binning, and quality assessment tools may result in MAGs that do not reflect single populations in nature.
Evans, Jacob T., Denef, Vincent J.
openaire +3 more sources
Dereplication of secondary metabolites from Sophora flavescens using an LC-MS/MS-based molecular networking strategy. [PDF]
Sci RepA dereplication strategy was developed for the screening of secondary metabolites from Sophora flavescens. The strategy consisted of 4 procedures.
Wang H, Ding H.
europepmc +2 more sources
Molecular Networking as a Dereplication Strategy [PDF]
Journal of Natural Products, 2013 A major goal in natural product discovery programs is to rapidly dereplicate known entities from complex biological extracts. We demonstrate here that molecular networking, an approach that organizes MS/MS data based on chemical similarity, is a powerful complement to traditional dereplication strategies.
Yang, Jane Y +15 more
openaire +4 more sources