Results 51 to 60 of about 13,781 (277)

Chemodiversity and Anti-Leukemia Effect of Metabolites from Penicillium setosum CMLD 18

Metabolites, 2022
Penicillium setosum represents a Penicillium species recently described, with little up-to-date information about its metabolic and biological potential. Due to this scenario, we performed chemical and biological studies of P.
Ana Calheiros de Carvalho, Cauê Santos Lima, Heron Fernandes Vieira Torquato, André Tarsis Domiciano, Sebastião da Cruz Silva, Lucas Magalhães de Abreu, Miriam Uemi, Edgar Julian Paredes-Gamero, Paulo Cezar Vieira, Thiago André Moura Veiga, Lívia Soman de Medeiros   +10 more
doaj   +1 more source

Dereplication, Annotation, and Characterization of 74 Potential Antimicrobial Metabolites from Penicillium Sclerotiorum Using t-SNE Molecular Networks

Metabolites, 2021
Microorganisms associated with termites are an original resource for identifying new chemical scaffolds or active metabolites. A molecular network was generated from a collection of strain extracts analyzed by liquid chromatography coupled to tandem high-
Téo Hebra, Nicolas Elie, Salomé Poyer, Elsa Van Elslande, David Touboul, Véronique Eparvier   +5 more
doaj   +1 more source

The importance of mass spectrometric dereplication in fungal secondary metabolite analysis [PDF]

, 2015
Having entered the Genomic Era, it is now evident that the biosynthetic potential of filamentous fungi is much larger than was thought even a decade ago.
Larsen, Thomas Ostenfeld, Nielsen, Kristian Fog   +1 more
core   +2 more sources

MS/MS-Based Molecular Networking: An Efficient Approach for Natural Products Dereplication

Molecules, 2022
Natural products (NPs) have historically played a primary role in the discovery of small-molecule drugs. However, due to the advent of other methodologies and the drawbacks of NPs, the pharmaceutical industry has largely declined in interest regarding ...
Guo-Fei Qin, Xiao Zhang, Feng Zhu, Zong-Qing Huo, Q. Yao, Qun Feng, Zhong Liu, Gui-min Zhang, Jing-chun Yao, Hongbao Liang   +9 more
semanticscholar   +1 more source

Sherlock—A Free and Open-Source System for the Computer-Assisted Structure Elucidation of Organic Compounds from NMR Data

Molecules, 2023
The structure elucidation of small organic molecules (
Michael Wenk, Jean-Marc Nuzillard, Christoph Steinbeck   +2 more
doaj   +1 more source

Dereplication of antimicrobial biosurfactants from marine bacteria using molecular networking [PDF]

Scientific Reports, 2021
AbstractBiosurfactants are amphiphilic surface-active molecules of microbial origin principally produced by hydrocarbon-degrading bacteria; in addition to the bioremediation properties, they can also present antimicrobial activity. The present study highlights the chemical characterization and the antimicrobial activities of biosurfactants produced by ...
Albert D. Patiño, Manuela Montoya-Giraldo, Marynes Quintero, Lizbeth L. López-Parra, Lina M. Blandón, Javier Gómez-León   +5 more
openaire   +3 more sources

Natural product diversity of actinobacteria in the Atacama Desert [PDF]

, 2018
Natural Product diversityPeer reviewedPublisher ...
Ebel, Rainer, Jaspars, Marcel, Rateb, Mostafa E.   +2 more
core   +3 more sources

Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE

Journal of Natural Products, 2022
Strategies for natural product dereplication are continually evolving, essentially in lock step with advances in MS and NMR techniques. MADByTE is a new platform designed to identify common structural features between samples in complex extract libraries
L. Flores-Bocanegra, Zeinab Y. Al Subeh, Joseph M. Egan, T. El-Elimat, H. Raja, J. Burdette, C. Pearce, Roger G. Linington, N. Oberlies   +8 more
semanticscholar   +1 more source

Rapid Identification of Common Secondary Metabolites of Medicinal Herbs Using High-Performance Liquid Chromatography with Evaporative Light Scattering Detector in Extracts

Metabolites, 2021
The discovery and identification of novel natural products of medicinal importance in the herbal medicine industry becomes a challenge. The complexity of this process can be reduced by dereplication strategies.
Kiran Ali, Arslan Ali, Muhammad Noman Khan, Saeedur Rahman, Shaheen Faizi, Muhammad Shaiq Ali, Shaden A. M. Khalifa, Hesham R. El-Seedi, Syed Ghulam Musharraf   +8 more
doaj   +1 more source

Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. [PDF]

, 2017
Natural product screening programs have uncovered molecules from diverse natural sources with various biological activities and unique structures. However, much is yet underexplored and additional information is hidden in these exceptional collections ...
Ackermann, Gail, Alexandrov, Theodore, Amir, Amnon, Bandeira, Nuno, Dorrestein, Pieter C, Duggan, Brendan M, Garg, Neha, Gerwick, Lena, Gerwick, William H, Glukhov, Evgenia, Knight, Rob, Luzzatto-Knaan, Tal, Peng, Yao, Ryazanov, Sergey, Wang, Mingxun   +14 more
core   +3 more sources