Results 71 to 80 of about 13,781 (277)

Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression

mBio, 2021
Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic ...
Wonyong Kim, Rundong Liu, S. Woo, K. Kang, H. Park, Y. Yu, Hyung-Ho Ha, Seung-Yoon Oh, Ji Ho Yang, H. Kim, S. Yun, J. Hur   +11 more
semanticscholar   +1 more source

A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria [PDF]

, 2017
A marine-derived Stilbella fimetaria fungal strain was screened for new bioactive compounds based on two different approaches: (i) bio-guided approach using cytotoxicity and antimicrobial bioassays; and (ii) dereplication based approach using liquid ...
Andersen, Birgitte, de la Cruz, Mercedes, Díaz, Caridad, Frisvad, Jens Christian, Goidts, Violaine, Gotfredsen, Charlotte Held, Kildgaard, Sara, Larsen, Thomas Ostenfeld, Nielsen, Kristian Fog, Phillips, Emma, Subko, Karolina   +10 more
core   +1 more source

Secondary Metabolites Detected in Deep-Water Endemic Amphipods of Lake Baikal: Bacterial or Crustacean Origin? [PDF]

Journal of Stress Physiology & Biochemistry, 2017
The aim of the study was to conduct a dereplication analysis of crude extract of deepwater Baikal’s endemic amphipod species, Ommatogammarus albinus. Detected masses provide some evidence that amphipod’s extract might contain both host and microbiota ...
Protasov E.S., Axenov-Gribanov D.V., Shatilina Z.M., Voytsekhovskaya I.V., Vereshchagina K.P., Lubyaga Y.A., Rzhechitskiy Y.A., Shirokova Y.A., Timofeyev M.A.   +8 more
doaj  

iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments

Microorganisms, 2022
Oceans hold a stunning number of unique microorganisms, which remain unstudied by culture-dependent methods due to failures in establishing the right conditions for these organisms to grow.
José Diogo Neves Dos Santos, Susana Afonso João, Jesús Martín, F. Vicente, F. Reyes, O. Lage   +5 more
semanticscholar   +1 more source

Haemolymph of Cold-Adapted Baikal Endemic Amphipods as a Promising Source for Screening of Novel Natural Products [PDF]

Journal of Stress Physiology & Biochemistry, 2017
The aim of this study was to assess the possibility to use Baikal endemic amphipods as a source for screening of novel natural products. Analysis of amphipod’s E. verrucosus hemolymph by HPLC-MS was performed for the first time.
Axenov-Gribanov D.V. , Protasov E.S., Voytsekhovskaya I.V., Shatilina Z.M., Rzhechitskiy Y.A., Dimova M.D., Kostka D.V., Lubyaga Y.A., Timofeyev M.A.   +8 more
doaj  

Bioprospecting for Microorganisms in Peloids—Extreme Environment Known for Its Healing Properties

Frontiers in Marine Science, 2022
Seawater is an environment in which numerous microorganisms have evolved, some with a great potential for biotechnology. In recent years, many scientists have moved away from the assumption that the origin of life was in pools of water, and instead ...
Denis Vadlja, Maro Bujak, Rozelindra Čož-Rakovac, Marin Roje, Lara Čižmek, Anita Horvatić, Ema Svetličić, Ema Svetličić, Janko Diminić, Saša Rakovac, Damir Oros, Jurica Zucko, Antonio Starcevic   +12 more
doaj   +1 more source

Combination Strategy of Genetic Dereplication and Manipulation of Epigenetic Regulators Reveals a Novel Compound from Plant Endophytic Fungus

International Journal of Molecular Sciences, 2022
The strategies of genetic dereplication and manipulation of epigenetic regulators to activate the cryptic gene clusters are effective to discover natural products with novel structure in filamentous fungi.
Lu Yang, Guangwei Wu, Fanyue Meng, Huomiao Ran, Wenbing Yin, Wei Li, Xiaoqing Liu   +6 more
semanticscholar   +1 more source

Marine Biotechnology: A New Vision and Strategy for Europe [PDF]

, 2016
Marine Board-ESF The Marine Board provides a pan-European platform for its member organisations to develop common priorities, to advance marine research, and to bridge the gap between science and policy in order to meet future marine science challenges ...
Boyen, C., Børresen, T., Dobson, A., Höfle, M., Ianora, A., Jaspars, M., Kijjoa, A., Olafsen, J., Querellou, J., Rigos, G., Wijffels, R.H.   +10 more
core   +6 more sources

Targeted Isolation of Antibiofilm Compounds from Halophytic Endophyte Bacillus velezensis 7NPB-3B Using LC-HR-MS-Based Metabolomics

Microorganisms
The discovery of new natural products has become more challenging because of the re-isolation of compounds and the lack of new sources. Microbes dwelling in extreme conditions of high salinity and temperature are huge prospects for interesting natural ...
Sanju Singh, Elizabeth Nwagwu, Louise Young, Pankaj Kumar, Pramod B. Shinde, RuAngelie Edrada-Ebel   +5 more
doaj   +1 more source

Production of Fusaric Acid by Fusarium spp. in Pure Culture and in Solid Medium Co-Cultures. [PDF]

, 2016
The ability of fungi isolated from nails of patients suffering from onychomycosis to induce de novo production of bioactive compounds in co-culture was examined.
Bertrand, S., Bohni, N., Buyck, B., Gindro, K., Hofstetter, V., Monod, M., Schumpp, O., Wolfender, J.L.   +7 more
core   +3 more sources