Results 81 to 90 of about 13,781 (277)

Bioprospecting the Metabolome of Plant Urtica dioica L.: A Fast Dereplication and Annotation Workflow in Plant Metabolomics

Evidence-Based Complementary and Alternative Medicine, 2022
Plants have a pivotal role in ethnopharmacology, and their preparations are in use globally. However, getting down to the structure requires an effective workflow and mostly requires a time-consuming isolation process. Although bioassay-guided approaches
Keshab Bhattarai, Babita Paudel, S. Dahal, P. Yadav, Niraj Aryal, B. Baral, H. Bhattarai   +6 more
semanticscholar   +1 more source

Dereplication of New Saponins from Agave bracteosa

Plants
The genus Agave comprises over 400 species that are known for their diverse applications, which include being sources of fiber, food, and beverages. There has recently been increased interest in exploring the metabolic content of this genus, and in this respect, saponins are the main compounds of interest.
Francesca Guzzo, Alexandra G. Durán, Laura L. Rostoll, Francisco A. Macías, Ana M. Simonet   +4 more
openaire   +4 more sources

Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity

Advanced Science, EarlyView.
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye, Jialiang Kuang, Colin T. Bates, Arthur Escalas, Daliang Ning, Liyou Wu, Suo Liu, Sihang Deng, Jiesi Lei, Xiangwen Chen, Jennifer Pett‐Ridge, Malay Saha, Lauren Hale, Gangsheng Wang, Renmao Tian, Ying Fu, Yu Tang, Mary Firestone, Jizhong Zhou, Yunfeng Yang   +19 more
wiley   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

Dereplication approach for the first time isolation of tatarinowin a and pentadecanoic acid from Acorus calamus L. by using GC-MS

Natural Product Research, 2022
In the present study, we report herein the isolation of cadinane-type sesquiterpenoid, tatarinowin A (ACH-6), and pentadecanoic acid (ACH-8) from petroleum ether extract of rhizome of Acorus calamus L.
Chetan Kumar, Sabiyah Akhter, N. Satti, V. Gupta, S. Meena, R. Vishwakarma, Q. Hassan, M. Verma   +7 more
semanticscholar   +1 more source

GlobDB: a comprehensive species-dereplicated microbial genome resource

Bioinformatics Advances
Abstract Motivation Over the past years, substantial numbers of microbial species’ genomes have been deposited outside of conventional INSDC databases. Results The GlobDB aggregates 14 independent genomic catalogues ...
Daan R Speth, Nick Pullen, Samuel T N Aroney, Benjamin L Coltman, Jay Osvatic, Ben J Woodcroft, Thomas Rattei, Michael Wagner   +7 more
openaire   +2 more sources

Impacts of Biostimulants on Nitrous Oxide Emissions and the Soil Microbiome

Journal of Plant Nutrition and Soil Science, EarlyView.
Soil incubation experiment examining the influence of biostimulants on greenhouse gas emissions and the soil microbiome in fertilized soils. ABSTRACT Background Overapplication of nitrogenous fertilizer and enhanced microbial activity in agricultural soils are drivers of increasing greenhouse gas emissions.
Conor Blunt, Sean Storey, Andrea Fuchs, Rainer Melzer, Grace M. Cott   +4 more
wiley   +1 more source

Molecular Dereplication and In Vitro and In Silico Pharmacological Evaluation of Coriandrum sativum against Neuroblastoma Cells

Molecules, 2022
The aim of this study was to investigate the cytotoxic activity of the Coriandrum sativum (C. sativum) ethanolic extract (CSEE) in neuroblastoma cells, chemically characterize the compounds present in the CSEE, and predict the molecular interactions and ...
M. C. Marcucci, C. R. Oliveira, D. Spindola, A. A. Antunes, Leila Y. K. Santana, Victor Cavalaro, Isabelle B. Costa, A. C. de Carvalho, T. A. M. Veiga, Lívia S. Medeiros, Lucas Dos Santos Zamarioli, C. Gonçalves, M. F. Santos, S. S. Grecco, V. Y. Suzuki, L. Ferreira, D. M. Garcia   +16 more
semanticscholar   +1 more source

Anti-diabetic and anti-inflammatory bioactive hits from Coriaria intermedia Matsum. stem and Dracontomelon dao (Blanco) Merr. & Rolfe bark through bioassay-guided fractionation and liquid chromatography-tandem mass spectrometry

Frontiers in Pharmacology
Women have been found to be at a higher risk of morbidity and mortality from type 2 diabetes mellitus (T2DM) and asthma. α-Glucosidase inhibitors have been used to treat T2DM, and arachidonic acid 15-lipoxygenase (ALOX15) inhibitors have been suggested ...
Mavis Colleen Porciuncula Fabian, Rezzaira Marie Neduelan Astorga, Arnelson Arwin Gray Atis, Luis Agustin Elido Pilapil, Christine Chichioco Hernandez   +4 more
doaj   +1 more source

Dichlorinated and Brominated Rugulovasines, Ergot Alkaloids Produced by Talaromyces wortmannii

Molecules, 2015
UHPLC-DAD-HRMS based dereplication guided the detection of new halogenated alkaloids co-produced by Talaromyces wortmannii. From the fungal growth in large scale, the epimers 2,8-dichlororugulovasines A and B were purified and further identified by means
Lívia Soman de Medeiros, José Vinícius da Silva, Lucas Magalhães Abreu, Ludwig Heinrich Pfenning, Carolina Lúcia Silva, Sérgio Secherrer Thomasi, Tiago Venâncio, Karl-Heinz van Pée, Kristian Fog Nielsen, Edson Rodrigues-Filho   +9 more
doaj   +1 more source