Results 111 to 120 of about 17,521,865 (225)

Inductive Game Theory: A Basic Scenario [PDF]

open access: yes
The aim of this paper is to present the new theory called “inductive game theory”. A paper, published by one of the present authors with A. Matsui, discussed some part of inductive game theory in a specific game.
Mamoru Kaneko, J. Jude Kline
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Forecasting Irish Inflation: A Composite Leading Indicator [PDF]

open access: yes
This paper presents the results of research into the construction of a composite leading indicator of the Irish rate of inflation, as measured by the annual percentage change in the Consumer Price Index (CPI). It follows the work of Fagan and Fell (1994)
Mawdsley, Andrew, Quinn, Terry
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On generalized (α β)-derivations on lattices

open access: yes, 2012
Click on the link to view the abstract.Keywords: Lattice, modular lattice,distributive lattice, derivation, two sided α-derivation, generalized (α β d)-derivation.Quaestiones Mathematicae 34(2011), 417 ...
Ullah, Zafar, Chaudhry, Muhammad Anwar
core  

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