Results 141 to 150 of about 153,005 (198)

Gaps in Current Cardiometabolic Risk Assessment: A Review Supporting the Development of the C.O.R.E. Indicator Model. [PDF]

J Clin Med
Geraci C, Geraci G, Buonauro A, Morello V, La Rocca F, Esposito R.   +5 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Continuous indices to assess the phenotypic spectrum of kidney transplant rejection. [PDF]

Nat Commun
Vaulet T, Koshy P, Wellekens K, Aubert O, Bottomley C, Callemeyn J, Cleenders E, Coemans M, Cornell L, de Vries APJ, Divard G, Emonds MP, Florquin S, Haas M, Halloran PF, Kers J, Kuypers D, Muthukumar T, Pagliazzi A, Salvatore S, Thaunat O, Seshan SV, Van Loon E, Vanhoutte T, Böhmig GA, von Samson-Himmelstjerna FA, Willicombe M, Cherukuri A, Loupy A, Roufosse C, Naesens M.   +30 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Prediction of graft loss in living donor liver transplantation during the early postoperative period. [PDF]

PLoS Comput Biol
Yoshimura R, Nakamura N, Matsuura T, Toshima T, Fukuhara T, Aihara K, Fujiu K, Iwami S, Yoshizumi T.   +8 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Stabilizing Defect Visibility Under Overexposure in Fringe-Based Imaging via <i>γ</i> Nonlinearity Analysis. [PDF]

Sensors (Basel)
Ma X, Wang X, Zhai R, Jia Z, Zhang W, Zhao B, Guan C.   +6 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Reactive power planning based on a proposed voltage stability index in power systems with renewable energy resources. [PDF]

Sci Rep
Sonbol M, Abdalla OH, Shaheen AM, Fayek HH.   +3 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source