Results 81 to 90 of about 17,521,865 (225)

Average Gibbs energy per lattice defect: a thermodynamic derivation

open access: yes, 1997
The statistical thermodynamics of defects is discussed from the point of view of the thermodynamics of ideal solutions. This is used to derive equations for the average Gibbs free energy per defect and a comparison is made with a recent statistical ...
Landsberg, P.T.   +3 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The quest for the best consumer confidence indicator [PDF]

open access: yes
We search through all possible consumer confidence indicators in order to find the single indicator that has the highest correlation with private consumption growth.
Staffan Lindén, Andreas Jonsson
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

The Arbitrage Pricing Model: A Pedagogic Derivation and a Spreadsheet-Based Illustration [PDF]

open access: yes, 2016
This paper derives, from a pedagogic perspective, the Arbitrage Pricing Model, which is an important asset pricing model in modern finance. The derivation is based on the idea that, if a self-financed investment has no risk exposures, the payoff from the
Clarence C. Y. Kwan
core  

Evaluation Indicator Architecture Development for Industrial Automation Systems Using ISO15704 Annex B: GERAM

open access: yes, 2011
Nowadays, the Evaluation Indicator Architecture (EIA) is needed to measure the development level of Industrial Automation Systems (IAS). This paper provides a method to develop EIA for IAS based on GERAM.
Jun Li, Jian Zhou, Qing Li
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Derivations with conditions on polynomials

open access: yes, 2008
出版單位:真理大學[[abstract]]Let R be a prime ring with extended centroid C and f(X1; : : : ;Xt) a nonzero polynomial over C. Suppose that d is a nonzero derivation of R such that h d(f(x1; : : : ; xt)); f(x1; : : : ; xt) i k = 0 (d(f(x1; : : : ; xt)) 2 C) for ...
張志銘, Chang,Chi-ming
core  

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