Results 101 to 110 of about 6,462,700 (311)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

When Regenerative Medicine Faces the Challenges of Reproductive Medicine: A Review Study on Recent Advances in the Strategies for Derivation of Gametes from Stem Cells

open access: yesEuropean Medical Journal Reproductive Health, 2020
The murine model has allowed for the replication of all developmental stages of the mammalian germline in vitro, from embryonic stem cells to epiblast cells, primordial germ cells, and finally into functional haploid gametes.
María Gil Juliá, José V. Medrano
doaj  

Современные славянские языки в академической славистике: процессы, тенденции, коммуникация и деривация. Rec.: „Specyfika leksyki i słowotwórstwa języków słowiańskich na przełomie XX i XXI wieku" („Prace Slawistyczne – Slavica", 136), red. Zofia Rudnik-Karwatowa, Slawistyczny Ośrodek Wydawniczy, Warszawa 2012, 188 ss.

open access: yesStudia z Filologii Polskiej i Słowiańskiej, 2016
Modern Slavic languages and academic Slavic Studies: processes, tendencies, communication and derivation (review) The article is a review of the volume Specyfika leksyki i słowotwórstwa języków słowiańskich na przełomie XX i XXI wieku (“Prace ...
Валентина [Valentina] Г. [G.] Кульпина [Kul'pina]   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Morphologie und Semantik der "n"-Erweiterung bei "Muttern" und "Vatern" im Deutschen

open access: yesZeitschrift für Wortbildung, 2021
This paper deals with German kinship terms ending with the form n (Muttern, Vatern). Firstly, data from newspapers are presented that show that especially Muttern denotes very special meanings that can only be derived to a limited extent from the lexical
Alexander Werth
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Soft derivative

open access: yesBoletim da Sociedade Paranaense de Matemática
This study presents a comprehensive investigation of soft and upper (lower) soft derivatives within the framework of Molodtsov’s soft set theory, extending it through the introduction of novel and complementary notions: left and right soft derivatives.
Enginoğlu, Serdar, Arslan, Burak
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Elements with ambiguous morphological status: The marker -idz(o) in Griko

open access: yesQuaderns de Filologia: Estudis Lingüístics, 2014
In this paper, we examine some verbal formations with the element -idz(o) in Griko, a Greek-based dialect spoken in South Italy, and argue that -idz(o) has an ambiguous morphological status. We show that in some formations idz(o) seems to have undergone
Nikos Koutsoukos, Angela Ralli
doaj   +1 more source

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