Results 151 to 160 of about 303,092 (316)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
In this paper, we introduce notions of (n, m)-derivation-homomorphisms and Boolean n-derivations.
Li, Lingyue, Xu, Xiaowei
core
Prispevek predstavlja kvantitativne lastnosti v slovarju zajetega besedja, ki ga omogoča računalniški program SlovarRed 2.0, 2003 Tomaža Seliškarja in Sekcije za terminološke slovarje Inštituta za slovenski jezik Frana Ramovša, ZRC SAZU.
Irena STRAMLJIČ BREZNIK
doaj
Derived tame and derived wild algebras
We prove that every finite dimensional algebra over an algebraically closed field is either derived tame or derived wild. We also prove that any deformation of a derived tame algebra is derived tame.
openaire +5 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
On Constructing a Secure and Fast Key Derivation Function Based on Stream Ciphers
In order to protect electronic data, pseudorandom cryptographic keys generated by a standard function known as a key derivation function play an important role.
Alawatugoda, Janaka +2 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Nana Xu,1,2 Qiao Zhang,1,2 Guolan Wu,1,2 Duo Lv,1,2 Yunliang Zheng1,2 1Research Center of Clinical Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Provincial
Xu N, Zheng Y, Lv D, Wu G, Zhang Q
core

