Results 131 to 140 of about 303,092 (316)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

LA MODERNISATION LATINO-ROMANE DU LEXIQUE ROUMAIN. LE MODÈLE INTERNE [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2016
Latin Romance modernization of the Romanian literary vocabulary was attained, at the end of the 18th century, primarily by lexical borrowing and by calque.
Gheorghe CHIVU
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Derivation ranges

open access: yes, 1998
In this paper we obtain some sufficient and some necessary conditions that the identity be in the closure of the range of an inner derivation. We obtain some results concerning the intersection of the closure of the range of the inner derivation induced ...
Salah Mecheri, Mecheri, Salah
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Derivation languages and syntactical categories

open access: yes, 1975
Derivations in unrestricted phrase structure grammars are represented in terms of a string called a derivation word. The derivation word gives a very compact representation of the canonical (leftmost) derivation.
Hart, Johnson M.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Między gramatyką a słownikiem – 
słowotwórstwo w perspektywie glottodydaktycznej

open access: yesPostscriptum Polonistyczne, 2020
Knowledge of word formation is an important element of the grammatical competencies of native speakers. Studying forms and functions of derivates and practising using them is also extremely important for foreigners studying Polish.
Anna Seretny, Wiesław Stefańczyk
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Some New Optimal Skew Cyclic Codes With Derivation

open access: yesIEEE Access
Our study included a class of cyclic codes named $\delta _{\alpha,\zeta }-$ cyclic codes over the ring $\mathcal {R}=\mathbb {F}_{2^{m}} + u\mathbb {F}_{2^{m}}+u^{2}\mathbb {F}_{2^{m}}$ , where m is an odd positive integer with $u^{3}=1$ . These codes
Asia Noor   +3 more
doaj   +1 more source

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