Results 231 to 240 of about 5,342,052 (371)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Development and validation of a nomogram for predicting the incidence of infectious events in patients with idiopathic inflammatory myopathies. [PDF]

Front Immunol
Yang L, Fan G, Zhang L, Zhou B, Dai X, Ji Z, Ma L, Zhang Z, Chen H, Yu Q, Ma L, Jiang L, Sun Y.   +12 more
europepmc   +1 more source

Note on the present position of the Earth's magnetic axis derived from declination data alone [PDF]

, 1907
W. van Bemmelen
openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Development and validation of a dynamic nomogram for acute kidney injury prediction in ICU patients with acute heart failure. [PDF]

Front Med (Lausanne)
Feng LH, Su T, Huang L, Liao T, Lu Y, Wu L.   +5 more
europepmc   +1 more source

STUDIES IN NITRATION, IV.¹ NITRATION OF N-ACYL COMPOUNDS OF ANILINE DERIVED FROM CERTAIN POLYBASIC, ALIPHATIC AND AROMATIC ACIDS. [PDF]

, 1908
J. Bishop Tingle, F. C. Blanck
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Circulating proteomic biomarkers for cerebral amyloid angiopathy screening and risk stratification. [PDF]

Alzheimers Dement
Xu J, Su Y, Sha Y, Fu J, Yan T, Xu F, Tang H, Ying Y, Xia Y, Dong Q, Gurol ME, Ni J, Cheng X.   +12 more
europepmc   +1 more source

The infinitesimal model: Definition, derivation, and implications.

Theoretical Population Biology, 2017
N. Barton, A. Etheridge, A. Véber
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source