Results 191 to 200 of about 5,200,905 (357)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Learning discrete structures for cancer radiomics. [PDF]
Yang J+7 more
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
The Role of Morphological Information in Processing Pseudo-words in Italian L2 Learners: It's a Matter of Experience. [PDF]
Amenta S, Foppolo F, Badan L.
europepmc +1 more source
Deformations of Lie Algebras using σ-Derivations [PDF]
J. Hartwig+2 more
semanticscholar +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Quantitative electroencephalography in the diagnosis of dementia with Lewy bodies. [PDF]
Mahajan A+13 more
europepmc +1 more source
A Patterson Analysis derived from the Cyclol C2 Skeleton [PDF]
Dennis P. Riley
openalex +1 more source