Results 81 to 90 of about 61,031 (297)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

On derivations and generalized derivations of bitonic algebras

open access: yes, 2018
We introduce the notion of bitonic algebras as a generalization of dual BCCalgebras, and define the notion of (r,l)-derivations, (l,r)-derivations and generalized (r,l) and (l,r)-derivations on the bitonic algebras.
Şule Özbal, Yong Yon
core   +1 more source

On t-derivations of PMS-algebras [version 1; peer review: 2 approved]

open access: yesF1000Research
Background PMS algebras are a type of algebraic structure that has been studied extensively in recent years. They are a generalization of several other algebraic structures, such as Boolean algebras and MV-algebras.
Zelalem Teshome Wale   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Inner and Outer Derivations of FV8n [PDF]

open access: yesAdvances in Group Theory and Applications
Let F be a field of characteristic 0 or an odd rational prime p. In this article, we give an explicit classification of all the inner and outer derivations of the group algebra FV8n, where V8n is a group of order 8n (n a positive integer).
Praveen Manju, Rajendra Kumar Sharma
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Some Centrally Extended Derivations on Banach Algebras

open access: yesMathematics
In this article, we consider centrally extended derivations on Banach algebras. We first establish the stability of centrally extended derivations on Banach algebras.
Ick-Soon Chang, Jaiok Roh
doaj   +1 more source

Study of MV-algebras via derivations

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
The main goal of this paper is to give some representations of MV-algebras in terms of derivations. In this paper, we investigate some properties of implicative and difference derivations and give their characterizations in MV-algebras.
Wang Jun Tao, She Yan Hong, Qian Ting
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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