Results 191 to 200 of about 305,961 (299)

Calibrating the GAMIL3-1° climate model using a derivative-free optimization method [PDF]

Wenjun Liang, Simon F. B. Tett, Lijuan Li, Coralia Cartis, Danya Xu, Wenjie Dong, Junjie Huang   +6 more
openalex   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Virtual State Coupled Sliding Mode Control: An Energy Exchange Approach with Tunable Performance Trade-Off. [PDF]

Sensors (Basel)
Wang J, Wang J, Jing J, Zhao C, Zhang L.
europepmc   +1 more source

Bayesian nights: Optimizing night photography rendering with Bayesian derivative-free methods

Simone Zini, Marco Buzzelli
openalex   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

AI fragmentation-based optimization of Sorafenib derivatives targeting VEGFR2 for angiogenesis-related pathologies: a structure-based in-silico study. [PDF]

Sci Rep
Inan D, Karageçili S, Ali N.
europepmc   +1 more source

Direction of Arrival (DOA) Estimation in an Array of Antennas using Derivative-Free Methods

, 2015
Raees Muhammad Asif, Shahzada Alamgir, Junaid Ali Khan   +2 more
openalex   +1 more source

Methods for Network Optimization and Parallel Derivative-free Optimization.

, 2014
This thesis is divided into two parts that each is concerned with a specific problem. The problem under consideration in the first part is to find suitable graph representations, abstractions, cost measures and algorithms for calculating placements of unmanned aerial vehicles (UAVs) such that they can keep one or several static targets under constant ...
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Denoising and Baseline Correction of Low-Scan FTIR Spectra: A Benchmark of Deep Learning Models Against Traditional Signal Processing. [PDF]

Bioengineering (Basel)
Mokari A, Raghunathan S, Shydliukh A, Ryabchykov O, Krafft C, Bocklitz T.   +5 more
europepmc   +1 more source