Results 41 to 50 of about 305,961 (299)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Analysis of Traub’s Method for Cubic Polynomials

Axioms
The dynamical analysis of Kurchatov’s scheme is extended to Traub’s method. The difference here is that Traub’s method requires two additional starting points. Therefore, the map is three-dimensional instead of 2-D.
Beny Neta
doaj   +1 more source

Three-Step Derivative-Free Method of Order Six

Foundations, 2023
Derivative-free iterative methods are useful to approximate the numerical solutions when the given function lacks explicit derivative information or when the derivatives are too expensive to compute.
Sunil Kumar, Janak Raj Sharma, Ioannis K. Argyros, Samundra Regmi   +3 more
doaj   +1 more source

Full-low evaluation methods for derivative-free optimization

Optimization Methods and Software, 2022
We propose a new class of rigorous methods for derivative-free optimization with the aim of delivering efficient and robust numerical performance for functions of all types, from smooth to non-smooth, and under different noise regimes. To this end, we have developed Full-Low Evaluation methods, organized around two main types of iterations.
Albert S. Berahas, Oumaima Sohab, Luís Nunes Vicente   +2 more
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Discrete Gradient Method: Derivative-Free Method for Nonsmooth Optimization

Journal of Optimization Theory and Applications, 2007
The paper of A. M. Bagirov, B. Karasözen and M. Sezer is a valuable contribution to the numerical-algorithmical part of unconstrained continuous optimization, in fact, to its nonsmooth version, and the corresponding theory is provided, too. It stands in the tradition of nonsmooth analysis and optimization, but it benefits from some insight and ...
Bagirov, A. M., Karasözen, B., Sezer, M.   +2 more
openaire   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

On highly efficient derivative-free family of numerical methods for solving polynomial equation simultaneously

Advances in Difference Equations, 2021
A highly efficient new three-step derivative-free family of numerical iterative schemes for estimating all roots of polynomial equations is presented.
Mudassir Shams, Naila Rafiq, Nasreen Kausar, Praveen Agarwal, Choonkil Park, Nazir Ahmad Mir   +5 more
doaj   +1 more source