Results 61 to 70 of about 166,379 (315)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Scaling symmetry, renormalization, and time series modeling

open access: yes, 2013
We present and discuss a stochastic model of financial assets dynamics based on the idea of an inverse renormalization group strategy. With this strategy we construct the multivariate distributions of elementary returns based on the scaling with time of ...
Baldovin, Fulvio   +3 more
core   +1 more source

Analysis of a Four-Dimensional Hyperchaotic System Described by the Caputo–Liouville Fractional Derivative

open access: yesComplexity, 2020
A new four-dimensional hyperchaotic financial model is introduced. The novelties come from the fractional-order derivative and the use of the quadric function x4 in modeling accurately the financial market.
Ndolane Sene
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Has the statutory derivative claim fulfilled its objectives? The hypothetical director and CSR [PDF]

open access: yes, 2011
This article follows on from the discussion on establishing a prima facie case and the mandatory bars in derivative claims. First, the second stage of the test will be considered, covering the standard of proof and how the court as a hypothetical ...
Gibbs, David
core  

Review of the Fractional Black-Scholes Equations and Their Solution Techniques

open access: yesFractal and Fractional
The pioneering work in finance by Black, Scholes and Merton during the 1970s led to the emergence of the Black-Scholes (B-S) equation, which offers a concise and transparent formula for determining the theoretical price of an option. The establishment of
Hongmei Zhang   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Estimation of Ask and Bid Prices for Geometric Asian Options

open access: yesDiscrete Dynamics in Nature and Society, 2019
Traditional derivative pricing theories usually focus on the risk-neutral price or the equilibrium price. However, in highly competitive financial markets, we observed two prices which are called bid and ask prices; then the unique risk-neutral price ...
Tao Chen, Kaili Xiang, Xuemei Luo
doaj   +1 more source

THE LAW ABOUT SECURITIES MARKET AS A LAW ABOUT FINANCE MARKETS

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2018
The development of the Law about securities market is taking place not only in the direction of deeper regulation of the given market itself but  also in the direction of broader covering of other finance markets with  finance tools which differ from ...
Vladimir A. Galanov   +1 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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